Expression of CFAP20 in cancer - Summary

CANCER ATLAS

Gene description

Cilia and flagella associated protein 20

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA018195

Tissue	Cancer staining	Protein expression of normal tissue
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma

Tissue	Cancer staining	Protein expression of normal tissue
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary	A majority of skin, breast, gastric, colorectal and pancreatic cancers as well as several cervical, lung and liver cancers showed moderate to strong cytoplasmic staining. Remaining malignancies were weakly stained or negative.

GENE INFORMATION
Gene name	CFAP20 (HGNC Symbol)
Synonyms	C16orf80, fSAP23, GTL3
Description	Cilia and flagella associated protein 20 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q21
Chromosome location (bp)	58113588 - 58129450
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000070761 (version 83.38)
Entrez gene	29105
UniProt	Q9Y6A4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y6A4
Antibodypedia	CFAP20 antibodies

PROTEIN BROWSER

CFAP20-001	CFAP20-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CFAP20-001 ENSP00000262498 ENST00000262498	Q9Y6A4 [Direct mapping] Cilia- and flagella-associated protein 20 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005814 [centriole] GO:0005874 [microtubule] GO:0005929 [cilium] GO:0007275 [multicellular organismal development] GO:0018095 [protein polyglutamylation] GO:0036064 [ciliary basal body] GO:0044822 [poly(A) RNA binding] GO:0060271 [cilium morphogenesis] GO:0060296 [regulation of cilium beat frequency involved in ciliary motility] GO:0070062 [extracellular exosome] GO:2000147 [positive regulation of cell motility] GO:2000253 [positive regulation of feeding behavior] Show all	193 aa 22.8 kDa	No	0
CFAP20-007 ENSP00000455220 ENST00000565880	H3BPA3 [Direct mapping] Cilia- and flagella-associated protein 20 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		109 aa 12.4 kDa	No	0