Expression of CDH19 in cancer - Summary

CANCER ATLAS

Gene description

Cadherin 19, type 2

Protein class

Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA056332

GENE INFORMATION
Gene name	CDH19 (HGNC Symbol)
Synonyms	CDH7
Description	Cadherin 19, type 2 (HGNC Symbol)
Entrez gene summary	This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of cadherins may be associated with cancer formation. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2012]
Chromosome	18
Cytoband	q22.1
Chromosome location (bp)	66501083 - 66604138
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000071991 (version 83.38)
Entrez gene	28513
UniProt	Q9H159 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H159
Antibodypedia	CDH19 antibodies

PROTEIN BROWSER

CDH19-001	CDH19-003	CDH19-005	CDH19-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDH19-001 ENSP00000262150 ENST00000262150	Q9H159 [Direct mapping] Cadherin-19 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005886 [plasma membrane] GO:0007155 [cell adhesion] GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	772 aa 87 kDa	Yes	1
CDH19-003 ENSP00000401998 ENST00000454642	F8VVI9 [Direct mapping] Cadherin-19 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005886 [plasma membrane] GO:0007155 [cell adhesion] GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules] GO:0016020 [membrane] Show all	434 aa 48.8 kDa	No	0
CDH19-005 ENSP00000439593 ENST00000540086	Q9H159 [Direct mapping] Cadherin-19 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005886 [plasma membrane] GO:0007155 [cell adhesion] GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	490 aa 55.4 kDa	Yes	0
CDH19-006 ENSP00000464477 ENST00000580157	J3QS15 [Direct mapping] Cadherin-19 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		65 aa 7.7 kDa	Yes	0