Tissue expression of ACAP1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ACAP1
Gene description	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Protein class	Cancer-related genes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (lymph node)
GTEx:	Expressed in all
FANTOM5:	Tissue enhanced (tonsil, appendix)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (lymph node)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (tonsil, appendix)

GENE INFORMATION
Gene name	ACAP1 (HGNC Symbol)
Synonyms	CENTB1, KIAA0050
Description	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.1
Chromosome location (bp)	7336529 - 7351478
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000072818 (version 83.38)
Entrez gene	9744
UniProt	Q15027 (UniProt - Evidence at protein level)
neXtProt	NX_Q15027
Antibodypedia	ACAP1 antibodies

PROTEIN BROWSER

ACAP1-001	ACAP1-003	ACAP1-004	ACAP1-009	ACAP1-010	ACAP1-011	ACAP1-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACAP1-001 ENSP00000158762 ENST00000158762	Q15027 [Direct mapping] Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Show all	Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0043547 [positive regulation of GTPase activity] GO:0046872 [metal ion binding] GO:0055038 [recycling endosome membrane] Show all	740 aa 81.5 kDa	No	0
ACAP1-003 ENSP00000458173 ENST00000570457	I3L0K9 [Direct mapping] Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		148 aa 17 kDa	No	0
ACAP1-004 ENSP00000459422 ENST00000575425	I3L268 [Direct mapping] Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		101 aa 11.4 kDa	No	0
ACAP1-009 ENSP00000461314 ENST00000571471	I3L2Z4 [Direct mapping] Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		44 aa 5 kDa	No	0
ACAP1-010 ENSP00000460803 ENST00000574499	I3L3X6 [Direct mapping] Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		65 aa 7.4 kDa	No	0
ACAP1-011 ENSP00000460054 ENST00000575415	I3L2Z4 [Direct mapping] Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		44 aa 5 kDa	No	0
ACAP1-012 ENSP00000460735 ENST00000570504	I3L2Z4 [Direct mapping] Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		44 aa 5 kDa	No	0