Cell atlas - CYP2W1 - The Human Protein Atlas

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CYP2W1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CYP2W1
Gene description	Cytochrome P450, family 2, subfamily W, polypeptide 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (Hep G2, CACO-2)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (Hep G2, CACO-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CYP2W1 (HGNC Symbol)
Synonyms	FLJ20359, MGC34287
Description	Cytochrome P450, family 2, subfamily W, polypeptide 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	p22.3
Chromosome location (bp)	983199 - 989640
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000073067 (version 83.38)
Entrez gene	54905
UniProt	Q8TAV3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TAV3
Antibodypedia	CYP2W1 antibodies

PROTEIN BROWSER

CYP2W1-001	CYP2W1-002	CYP2W1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CYP2W1-001 ENSP00000310149 ENST00000308919	Q8TAV3 [Direct mapping] Cytochrome P450 2W1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0005737 [cytoplasm] GO:0005788 [endoplasmic reticulum lumen] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0006082 [organic acid metabolic process] GO:0006805 [xenobiotic metabolic process] GO:0008395 [steroid hydroxylase activity] GO:0009986 [cell surface] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0016712 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0042738 [exogenous drug catabolic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0043390 [aflatoxin B1 metabolic process] GO:0044281 [small molecule metabolic process] GO:0055114 [oxidation-reduction process] Show all	490 aa 53.8 kDa	Yes	0
CYP2W1-002 ENSP00000344178 ENST00000340150	A6NJ10 [Direct mapping] Cytochrome P450 2W1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0005737 [cytoplasm] GO:0006082 [organic acid metabolic process] GO:0008395 [steroid hydroxylase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0016712 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0042738 [exogenous drug catabolic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0055114 [oxidation-reduction process] Show all	408 aa 44.7 kDa	No	0
CYP2W1-005 ENSP00000392581 ENST00000415893	H7C015 [Direct mapping] Cytochrome P450 2W1 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0005737 [cytoplasm] GO:0006082 [organic acid metabolic process] GO:0008395 [steroid hydroxylase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0016712 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0042738 [exogenous drug catabolic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0055114 [oxidation-reduction process] Show all	288 aa 30.6 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.