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Liver cancer as well as several case of malignant melanomas, pancreatic, ovarian, gastric, colorectal and breast cancers showed moderate cytoplasmic immunoreactivity. The remaining malignant cells were negative or weakly stained.
Several cases of malignant melanomas, breast, colorectal and liver cancers exhibited moderate cytoplasmic and membranous positivity. Other cancers were in general weakly stained or negative.
GENE INFORMATION
Gene name
ALPK1 (HGNC Symbol)
Synonyms
FLJ22670, KIAA1527, Lak
Description
Alpha-kinase 1 (HGNC Symbol)
Entrez gene summary
This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
