Expression of TUBE1 in cancer - Summary

CANCER ATLAS

Gene description

Tubulin, epsilon 1

Protein class

FDA approved drug targets, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA032073	HPA032074

GENE INFORMATION
Gene name	TUBE1 (HGNC Symbol)
Synonyms	dJ142L7.2, FLJ22589, TUBE
Description	Tubulin, epsilon 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Jan 2009]
Chromosome	6
Cytoband	q21
Chromosome location (bp)	112070777 - 112087529
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000074935 (version 83.38)
Entrez gene	51175
UniProt	Q9UJT0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9UJT0
Antibodypedia	TUBE1 antibodies

PROTEIN BROWSER

TUBE1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TUBE1-001 ENSP00000357651 ENST00000368662	Q9UJT0 [Direct mapping] Tubulin epsilon chain Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000242 [pericentriolar material] GO:0003924 [GTPase activity] GO:0005200 [structural constituent of cytoskeleton] GO:0005525 [GTP binding] GO:0005874 [microtubule] GO:0007017 [microtubule-based process] GO:0007098 [centrosome cycle] GO:0008152 [metabolic process] GO:0043234 [protein complex] GO:0051258 [protein polymerization] Show all	475 aa 52.9 kDa	No	0