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WNT8B

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GENERAL INFORMATION

Gene name

 WNT8B

Gene description

 Wingless-type MMTV integration site family, member 8B

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (AF22, SCLC-21H)

Protein evidence

 Evidence at transcript level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (AF22, SCLC-21H)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 WNT8B

Synonyms

Description

 Wingless-type MMTV integration site family, member 8B (HGNC Symbol)

Entrez gene summary

 The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy. [provided by RefSeq, Jul 2008]

Chromosome

 10

Cytoband

 q24.31

Chromosome location (bp)

 100463041 - 100483744

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000075290 (version 83.38)

Entrez gene

 7479

UniProt

 Q93098 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q93098

Antibodypedia

 WNT8B antibodies

PROTEIN BROWSER
WNT8B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
WNT8B-001
ENSP00000340677
ENST00000343737
Q93098 [Direct mapping]
Protein Wnt-8b
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0005102 [receptor binding]
GO:0005109 [frizzled binding]
GO:0005576 [extracellular region]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007369 [gastrulation]
GO:0007399 [nervous system development]
GO:0016055 [Wnt signaling pathway]
GO:0030182 [neuron differentiation]
GO:0032355 [response to estradiol]
GO:0032526 [response to retinoic acid]
GO:0045165 [cell fate commitment]
GO:0048263 [determination of dorsal identity]
GO:0071300 [cellular response to retinoic acid]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
Show all
 351 aa
38.7 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.