Cell atlas - SEC31B - The Human Protein Atlas

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SEC31B

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoli
	Nucleus
	Vesicles

Human cell
	Cytosol
	Nucleoli
	Nucleoplasm
	Vesicles

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GENERAL INFORMATION
Gene name	SEC31B
Gene description	SEC31 homolog B, COPII coat complex component
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol & vesicles. In addition localized to the nucleus & nucleoli.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved), Cytosol (approved)
Additional location	In addition localized to the Nucleus (approved), Nucleoli (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA060052
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol & vesicles. In addition localized to the nucleus & nucleoli.

Main location

Vesicles (approved), Cytosol (approved)

Additional location

Nucleus (approved), Nucleoli (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA060052	HEK 293	Nucleus
			Vesicles
			Cytosol
	HPA060052	HeLa	Nucleus
			Vesicles
			Cytosol
	HPA060052	U-2 OS	Nucleus
			Nucleoli
			Vesicles
			Cytosol

GENE INFORMATION
Gene name	SEC31B (HGNC Symbol)
Synonyms	DKFZP434M183, SEC31B-1, SEC31L2
Description	SEC31 homolog B, COPII coat complex component (HGNC Symbol)
Entrez gene summary	This gene encodes a protein of unknown function. The protein has moderate similarity to rat VAP1 protein which is an endosomal membrane-associated protein, containing a putative Ca2+/calmodulin-dependent kinase II phosphorylation site. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q24.31
Chromosome location (bp)	100486642 - 100519864
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000075826 (version 83.38)
Entrez gene	25956
UniProt	Q9NQW1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQW1
Antibodypedia	SEC31B antibodies

PROTEIN BROWSER

SEC31B-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SEC31B-003 ENSP00000359370 ENST00000370345	Q9NQW1 [Direct mapping] Protein transport protein Sec31B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0016192 [vesicle-mediated transport] GO:0030120 [vesicle coat] Show all	1179 aa 128.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.