Fields »
ABOUT
HELP
BLOG
EXOSC7

CANCER ATLAS

Gene description

 Exosome component 7

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA036182
HPA057980

GENE INFORMATION

Gene name

 EXOSC7 (HGNC Symbol)

Synonyms

 EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p

Description

 Exosome component 7 (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 p21.31

Chromosome location (bp)

 44975241 - 45036066

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000075914 (version 83.38)

Entrez gene

 23016

UniProt

 Q15024 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15024

Antibodypedia

 EXOSC7 antibodies

PROTEIN BROWSER
EXOSC7-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
EXOSC7-001
ENSP00000265564
ENST00000265564
Q15024 [Direct mapping]
Exosome complex component RRP42
A0A024R2P7 [Target identity:100%; Query identity:100%]
Exosome component 7, isoform CRA_a
Show all
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000175 [3'-5'-exoribonuclease activity]
GO:0000176 [nuclear exosome (RNase complex)]
GO:0000177 [cytoplasmic exosome (RNase complex)]
GO:0000178 [exosome (RNase complex)]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000467 [exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006364 [rRNA processing]
GO:0006401 [RNA catabolic process]
GO:0010467 [gene expression]
GO:0017091 [AU-rich element binding]
GO:0034427 [nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5']
GO:0034473 [U1 snRNA 3'-end processing]
GO:0034475 [U4 snRNA 3'-end processing]
GO:0034476 [U5 snRNA 3'-end processing]
GO:0043488 [regulation of mRNA stability]
GO:0043928 [exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay]
GO:0044822 [poly(A) RNA binding]
GO:0071028 [nuclear mRNA surveillance]
GO:0071035 [nuclear polyadenylation-dependent rRNA catabolic process]
GO:0071038 [nuclear polyadenylation-dependent tRNA catabolic process]
GO:0071042 [nuclear polyadenylation-dependent mRNA catabolic process]
Show all
 291 aa
31.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.