Expression of GTF3C1 in cancer - Summary

CANCER ATLAS

Gene description

General transcription factor IIIC, polypeptide 1, alpha 220kDa

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA051617

GENE INFORMATION
Gene name	GTF3C1 (HGNC Symbol)
Synonyms	TFIIIC220
Description	General transcription factor IIIC, polypeptide 1, alpha 220kDa (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p12.1
Chromosome location (bp)	27459555 - 27549913
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000077235 (version 83.38)
Entrez gene	2975
UniProt	Q12789 (UniProt - Evidence at protein level)
neXtProt	NX_Q12789
Antibodypedia	GTF3C1 antibodies

PROTEIN BROWSER

GTF3C1-001	GTF3C1-002	GTF3C1-008	GTF3C1-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GTF3C1-001 ENSP00000348510 ENST00000356183	Q12789 [Direct mapping] General transcription factor 3C polypeptide 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000127 [transcription factor TFIIIC complex] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0006351 [transcription, DNA-templated] GO:0006383 [transcription from RNA polymerase III promoter] GO:0009303 [rRNA transcription] GO:0009304 [tRNA transcription] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0030529 [ribonucleoprotein complex] GO:0042791 [5S class rRNA transcription from RNA polymerase III type 1 promoter] GO:0042797 [tRNA transcription from RNA polymerase III promoter] Show all	2109 aa 238.9 kDa	No	1
GTF3C1-002 ENSP00000455417 ENST00000561623	Q12789 [Direct mapping] General transcription factor 3C polypeptide 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000127 [transcription factor TFIIIC complex] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0006351 [transcription, DNA-templated] GO:0006383 [transcription from RNA polymerase III promoter] GO:0009303 [rRNA transcription] GO:0009304 [tRNA transcription] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0042791 [5S class rRNA transcription from RNA polymerase III type 1 promoter] GO:0042797 [tRNA transcription from RNA polymerase III promoter] Show all	2084 aa 236.3 kDa	No	1
GTF3C1-008 ENSP00000457449 ENST00000569653	H3BU37 [Direct mapping] General transcription factor 3C polypeptide 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		214 aa 24.1 kDa	No	0
GTF3C1-011 ENSP00000456187 ENST00000568569	H3BRD0 [Direct mapping] General transcription factor 3C polypeptide 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		181 aa 21 kDa	No	0