Cell atlas - ACER3 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ACER3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	ACER3
Gene description	Alkaline ceramidase 3
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ACER3 (HGNC Symbol)
Synonyms	APHC, FLJ11238, PHCA
Description	Alkaline ceramidase 3 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q13.5
Chromosome location (bp)	76860867 - 77026797
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000078124 (version 83.38)
Entrez gene	55331
UniProt	Q9NUN7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NUN7
Antibodypedia	ACER3 antibodies

PROTEIN BROWSER

ACER3-001	ACER3-006	ACER3-007	ACER3-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACER3-001 ENSP00000434480 ENST00000532485	Q9NUN7 [Direct mapping] Alkaline ceramidase 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005789 [endoplasmic reticulum membrane] GO:0006665 [sphingolipid metabolic process] GO:0006672 [ceramide metabolic process] GO:0008284 [positive regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0016811 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides] GO:0030148 [sphingolipid biosynthetic process] GO:0030173 [integral component of Golgi membrane] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0044281 [small molecule metabolic process] GO:0046512 [sphingosine biosynthetic process] GO:0070774 [phytoceramidase activity] GO:0071602 [phytosphingosine biosynthetic process] Show all	267 aa 31.6 kDa	No	7
ACER3-006 ENSP00000431149 ENST00000526597	B7Z2V2 [Direct mapping] Alkaline ceramidase 3; cDNA FLJ57303, highly similar to Alkaline phytoceramidase (EC 3.5.1.-); cDNA, FLJ79019, highly similar to Alkaline phytoceramidase (EC 3.5.1.-) Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006672 [ceramide metabolic process] GO:0016021 [integral component of membrane] GO:0016811 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides] Show all	172 aa 20.6 kDa	No	4
ACER3-007 ENSP00000436252 ENST00000533873	B7Z2Q2 [Direct mapping] Alkaline ceramidase 3; cDNA FLJ50957, highly similar to Alkaline phytoceramidase (EC 3.5.1.-) Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006672 [ceramide metabolic process] GO:0016021 [integral component of membrane] GO:0016811 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides] Show all	230 aa 27.4 kDa	No	6
ACER3-010 ENSP00000435733 ENST00000534206	E9PIN9 [Direct mapping] Alkaline ceramidase 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006672 [ceramide metabolic process] GO:0016021 [integral component of membrane] GO:0016811 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides] Show all	205 aa 24.2 kDa	No	6

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.