Expression of PKD2L2 in cancer - Summary

CANCER ATLAS

Gene description

Polycystic kidney disease 2-like 2

Protein class

Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041903	HPA043634

GENE INFORMATION
Gene name	PKD2L2 (HGNC Symbol)
Synonyms	TRPP5
Description	Polycystic kidney disease 2-like 2 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q31.2
Chromosome location (bp)	137887968 - 137942747
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000078795 (version 83.38)
Entrez gene	27039
UniProt	Q9NZM6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NZM6
Antibodypedia	PKD2L2 antibodies

PROTEIN BROWSER

PKD2L2-001	PKD2L2-002	PKD2L2-005	PKD2L2-006	PKD2L2-007	PKD2L2-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PKD2L2-001 ENSP00000424725 ENST00000508883	Q9NZM6 [Direct mapping] Polycystic kidney disease 2-like 2 protein Show all	Voltage-gated ion channels Transient Receptor Potential Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005262 [calcium channel activity] GO:0005509 [calcium ion binding] GO:0008150 [biological_process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0050982 [detection of mechanical stimulus] GO:0070588 [calcium ion transmembrane transport] Show all	624 aa 73.8 kDa	No	6
PKD2L2-002 ENSP00000425513 ENST00000502810	Q9NZM6 [Direct mapping] Polycystic kidney disease 2-like 2 protein Show all	Voltage-gated ion channels Transient Receptor Potential Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0005262 [calcium channel activity] GO:0005509 [calcium ion binding] GO:0008150 [biological_process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0050982 [detection of mechanical stimulus] GO:0070588 [calcium ion transmembrane transport] Show all	602 aa 71.3 kDa	No	7
PKD2L2-005 ENSP00000424885 ENST00000503015	D6RF71 [Direct mapping] Polycystic kidney disease 2-like 2 protein Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005262 [calcium channel activity] GO:0016020 [membrane] GO:0050982 [detection of mechanical stimulus] GO:0070588 [calcium ion transmembrane transport] Show all	182 aa 21.3 kDa	No	0
PKD2L2-006 ENSP00000423382 ENST00000508638	Q9NZM6 [Direct mapping] Polycystic kidney disease 2-like 2 protein Show all	Voltage-gated ion channels Transient Receptor Potential Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005262 [calcium channel activity] GO:0005509 [calcium ion binding] GO:0008150 [biological_process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0050982 [detection of mechanical stimulus] GO:0070588 [calcium ion transmembrane transport] Show all	523 aa 62.2 kDa	No	4
PKD2L2-007 ENSP00000423926 ENST00000511176	D6RBX8 [Direct mapping] Polycystic kidney disease 2-like 2 protein Show all	Predicted intracellular proteins Show all	GO:0005262 [calcium channel activity] GO:0016020 [membrane] GO:0050982 [detection of mechanical stimulus] GO:0070588 [calcium ion transmembrane transport] Show all	84 aa 9.9 kDa	No	0
PKD2L2-008 ENSP00000290431 ENST00000290431	Q9NZM6 [Direct mapping] Polycystic kidney disease 2-like 2 protein Show all	Voltage-gated ion channels Transient Receptor Potential Channels Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005262 [calcium channel activity] GO:0005509 [calcium ion binding] GO:0008150 [biological_process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0050982 [detection of mechanical stimulus] GO:0070588 [calcium ion transmembrane transport] Show all	613 aa 72.5 kDa	No	6