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MYH7B

GENERAL INFORMATION

Gene name

 MYH7B

Gene description

 Myosin, heavy chain 7B, cardiac muscle, beta

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (skeletal muscle, heart muscle, testis)
GTEx:Group enriched (heart muscle, testis, skeletal muscle)
FANTOM5:Group enriched (heart muscle, skeletal muscle)

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (skeletal muscle, heart muscle, testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (heart muscle, testis, skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (heart muscle, skeletal muscle)

GENE INFORMATION

Gene name

 MYH7B (HGNC Symbol)

Synonyms

 dJ756N5.1, KIAA1512, MHC14, MYH14

Description

 Myosin, heavy chain 7B, cardiac muscle, beta (HGNC Symbol)

Entrez gene summary

 The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010]

Chromosome

 20

Cytoband

 q11.22

Chromosome location (bp)

 34975403 - 35002437

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000078814 (version 83.38)

Entrez gene

 57644

UniProt

 A7E2Y1 (UniProt - Evidence at protein level)

neXtProt

 NX_A7E2Y1

Antibodypedia

 MYH7B antibodies

PROTEIN BROWSER
MYH7B-001
MYH7B-004
MYH7B-005
MYH7B-006
MYH7B-007
MYH7B-008
MYH7B-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MYH7B-001
ENSP00000262873
ENST00000262873
A7E2Y1 [Direct mapping]
Myosin-7B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0016459 [myosin complex]
GO:0032982 [myosin filament]
Show all
 1983 aa
225.8 kDa 		No 0
MYH7B-004
ENSP00000395858
ENST00000446156
Q5JW48 [Direct mapping]
Myosin-7B
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 144 aa
16.5 kDa 		No 0
MYH7B-005
ENSP00000409103
ENST00000453028
Q5JW46 [Direct mapping]
Myosin-7B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 122 aa
14.3 kDa 		No 0
MYH7B-006
ENSP00000391939
ENST00000435272
Q5JW49 [Direct mapping]
Myosin-7B
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 149 aa
16.7 kDa 		No 0
MYH7B-007
ENSP00000412594
ENST00000433934
Q5JW47 [Direct mapping]
Myosin-7B
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 143 aa
16.1 kDa 		No 0
MYH7B-008
ENSP00000396368
ENST00000456649
Q5JW45 [Direct mapping]
Myosin-7B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 149 aa
16.7 kDa 		No 0
MYH7B-201
ENSP00000483640
ENST00000618182
A0A087X0T3 [Direct mapping]
Myosin-7B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 1982 aa
225.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.