Cell atlas - BPIFB2 - The Human Protein Atlas

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BPIFB2

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Vesicles

Human cell
	Vesicles

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GENERAL INFORMATION
Gene name	BPIFB2
Gene description	BPI fold containing family B, member 2
Protein class	Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to vesicles.
RNA cell category	Cell line enriched (Hep G2)
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA049491
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (Hep G2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to vesicles.

Main location

Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA049491	HeLa	Vesicles
	HPA049491	Hep G2	Vesicles
	HPA049491	U-2 OS	Vesicles

GENE INFORMATION
Gene name	BPIFB2 (HGNC Symbol)
Synonyms	BPIL1, C20orf184, dJ726C3.2, LPLUNC2
Description	BPI fold containing family B, member 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the lipid transfer/lipopolysaccharide binding protein (LT/LBP) gene family. It is highly expressed in hypertrophic tonsils. This gene and three other members of the LT/LBP gene family form a cluster on the long arm of chromosome 20. [provided by RefSeq, Jul 2008]
Chromosome	20
Cytoband	q11.21
Chromosome location (bp)	33007600 - 33023709
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000078898 (version 83.38)
Entrez gene	80341
UniProt	Q8N4F0 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N4F0
Antibodypedia	BPIFB2 antibodies

PROTEIN BROWSER

BPIFB2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BPIFB2-001 ENSP00000170150 ENST00000170150	Q8N4F0 [Direct mapping] BPI fold-containing family B member 2 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005615 [extracellular space] GO:0008289 [lipid binding] GO:0070062 [extracellular exosome] Show all	458 aa 49.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.