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Few cases of urothelial cancers showed moderate to strong cytoplasmic staining. Rare cases of ovarian cancers displayed moderate membranous staining while thyroid and prostate cancers displayed moderate cytoplasmic staining. Most remaining tumor cells were negative.
A fraction of tumor cells in a rare case of ovarian cancer displayed strong cytoplasmic staining while papillary adenocarcinoma of thyroid showed moderate cytoplasmic and nuclear staining. Remaining tumor cells were mostly negative.
GENE INFORMATION
Gene name
RABL2B
Synonyms
Description
RAB, member of RAS oncogene family-like 2B (HGNC Symbol)
Entrez gene summary
The RABL2B protein is a member of the RAB gene family which belongs to the RAS GTPase superfamily. RABL2B is located within a subtelomeric region of 22q13.3. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]