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Most malignancies showed weak to moderate cytoplasmic positivity. Strong staining was observed in in thyroid cancers. Malignant gliomas, cervical, skin and lung cancers were generally negative or weakly stained.
Testicular cancers displayed moderate to strong cytoplasmic immunoreactivity. Remaining malignant cells were weakly stained or negative.
GENE INFORMATION
Gene name
DDX43 (HGNC Symbol)
Synonyms
CT13, DKFZp434H2114, HAGE
Description
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression. [provided by RefSeq, Jul 2008]