Expression of EXD2 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Exonuclease 3'-5' domain containing 2

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA002906	HPA005848

GENE INFORMATION
Gene name	EXD2 (HGNC Symbol)
Synonyms	C14orf114, EXDL2, FLJ10738
Description	Exonuclease 3'-5' domain containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q24.1
Chromosome location (bp)	69191511 - 69244020
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000081177 (version 83.38)
Entrez gene	55218
UniProt	Q9NVH0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NVH0
Antibodypedia	EXD2 antibodies

PROTEIN BROWSER

EXD2-001	EXD2-002	EXD2-003	EXD2-005	EXD2-006	EXD2-007	EXD2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EXD2-001 ENSP00000386915 ENST00000409014	Q9NVH0 [Direct mapping] Exonuclease 3'-5' domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006139 [nucleobase-containing compound metabolic process] GO:0008408 [3'-5' exonuclease activity] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	496 aa 56.3 kDa	No	0
EXD2-002 ENSP00000387331 ENST00000409018	Q9NVH0 [Direct mapping] Exonuclease 3'-5' domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006139 [nucleobase-containing compound metabolic process] GO:0008408 [3'-5' exonuclease activity] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	621 aa 70.4 kDa	No	1
EXD2-003 ENSP00000409089 ENST00000413191	C9JLF4 [Direct mapping] Exonuclease 3'-5' domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006139 [nucleobase-containing compound metabolic process] GO:0008408 [3'-5' exonuclease activity] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	114 aa 12.4 kDa	No	0
EXD2-005 ENSP00000386632 ENST00000409949	Q9NVH0 [Direct mapping] Exonuclease 3'-5' domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006139 [nucleobase-containing compound metabolic process] GO:0008408 [3'-5' exonuclease activity] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	496 aa 56.3 kDa	No	0
EXD2-006 ENSP00000386839 ENST00000409242	Q9NVH0 [Direct mapping] Exonuclease 3'-5' domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006139 [nucleobase-containing compound metabolic process] GO:0008408 [3'-5' exonuclease activity] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	496 aa 56.3 kDa	No	0
EXD2-007 ENSP00000386762 ENST00000409675	Q9NVH0 [Direct mapping] Exonuclease 3'-5' domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006139 [nucleobase-containing compound metabolic process] GO:0008408 [3'-5' exonuclease activity] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	496 aa 56.3 kDa	No	0
EXD2-201 ENSP00000313140 ENST00000312994	Q9NVH0 [Direct mapping] Exonuclease 3'-5' domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006139 [nucleobase-containing compound metabolic process] GO:0008408 [3'-5' exonuclease activity] GO:0090305 [nucleic acid phosphodiester bond hydrolysis] Show all	621 aa 70.4 kDa	No	1