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Most cancers displayed moderate to strong cytoplasmic staining. Several gliomas, lymphomas, carcinoid, renal, cervical, skin, breast, prostate and endometrial cancers were weakly stained or negative.
Most cancer tissues showed weak to moderate cytoplasmic positivity with additional membranous immunoreactivity in several cases. A few squamous cell carcinomas along with a single case of high grade glioma and urothelial cancer were strongly stained. Gliomas, lymphomas, breast, thyroid, liver and testicular cancers were in general negative.
GENE INFORMATION
Gene name
SLC13A1 (HGNC Symbol)
Synonyms
NAS1, NaSi-1
Description
Solute carrier family 13 (sodium/sulfate symporter), member 1 (HGNC Symbol)