Expression of COL19A1 in cancer - Summary

CANCER ATLAS

Gene description

Collagen, type XIX, alpha 1

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042422

GENE INFORMATION
Gene name	COL19A1
Synonyms
Description	Collagen, type XIX, alpha 1 (HGNC Symbol)
Entrez gene summary	This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	q13
Chromosome location (bp)	69866571 - 70209976
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000082293 (version 83.38)
Entrez gene	1310
UniProt	Q14993 (UniProt - Evidence at protein level)
neXtProt	NX_Q14993
Antibodypedia	COL19A1 antibodies

PROTEIN BROWSER

COL19A1-001	COL19A1-003	COL19A1-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COL19A1-001 ENSP00000480474 ENST00000620364	Q14993 [Direct mapping] Collagen alpha-1(XIX) chain Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Show all	GO:0001501 [skeletal system development] GO:0005201 [extracellular matrix structural constituent] GO:0005576 [extracellular region] GO:0005578 [proteinaceous extracellular matrix] GO:0005581 [collagen trimer] GO:0005788 [endoplasmic reticulum lumen] GO:0007155 [cell adhesion] GO:0007519 [skeletal muscle tissue development] GO:0016337 [single organismal cell-cell adhesion] GO:0022617 [extracellular matrix disassembly] GO:0030154 [cell differentiation] GO:0030198 [extracellular matrix organization] GO:0030574 [collagen catabolic process] GO:0030674 [protein binding, bridging] Show all	1142 aa 115.2 kDa	Yes	0
COL19A1-003 ENSP00000416556 ENST00000455415	Q5JVU1 [Direct mapping] Collagen alpha-1(XIX) chain Show all	Predicted intracellular proteins Show all		36 aa 3.8 kDa	No	0
COL19A1-004 ENSP00000479481 ENST00000478620	A0A087WVJ7 [Direct mapping] Collagen alpha-1(XIX) chain Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		60 aa 7 kDa	Yes	0