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Several cases of prostate cancers along with cases of colorectal, skin, urothelial and renal cancers exhibited moderate to strong cytoplasmic and membranous positivity. Remaining cancer cells were generally negative.
Most of the cancer tissues displayed weak to moderate cytoplasmic and/or membranous positivity. Nuclear staining was observed in melanomas. Gliomas along with several cases of lymphomas, ovarian, endometrial, skin and liver cancers were negative.