Tissue expression of ZNF586 - Summary - The Human Protein Atlas

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ZNF586

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ZNF586
Gene description	Zinc finger protein 586
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in several tissues, mainly immune cells.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Antibody staining in cells/structures not annotated, view images.
Reliability score	Approved based on 1 antibody. HPA060782
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ZNF586 (HGNC Symbol)
Synonyms	FLJ20070
Description	Zinc finger protein 586 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.43
Chromosome location (bp)	57769655 - 57819939
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000083828 (version 83.38)
Entrez gene	54807
UniProt	Q9NXT0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NXT0
Antibodypedia	ZNF586 antibodies

PROTEIN BROWSER

ZNF586-001	ZNF586-002	ZNF586-003	ZNF586-004	ZNF586-005	ZNF586-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF586-001 ENSP00000379454 ENST00000396150	Q9NXT0 [Direct mapping] Zinc finger protein 586 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	210 aa 22.8 kDa	No	0
ZNF586-002 ENSP00000379458 ENST00000396154	Q9NXT0 [Direct mapping] Zinc finger protein 586 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	402 aa 46.4 kDa	No	0
ZNF586-003 ENSP00000375583 ENST00000391702	Q9NXT0 [Direct mapping] Zinc finger protein 586 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	359 aa 41.7 kDa	No	0
ZNF586-004 ENSP00000470397 ENST00000598885	M0QZ99 [Direct mapping] Zinc finger protein 586 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	101 aa 10.7 kDa	No	0
ZNF586-005 ENSP00000471663 ENST00000598183	M0R166 [Direct mapping] Zinc finger protein 586 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	76 aa 8.4 kDa	No	0
ZNF586-006 ENSP00000472972 ENST00000599802	M0R336 [Direct mapping] Zinc finger protein 586 Show all	Predicted intracellular proteins Show all		23 aa 2.4 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.