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Most cancer cells displayed moderate cytoplasmic immunoreactivity, often with a granular pattern. Several cases of renal cancers along with a few cases of prostate and endometrial cancers were strongly stained. Several cases of lymphomas, gliomas and ovarian cancers were weakly stained or negative.
GENE INFORMATION
Gene name
STARD7 (HGNC Symbol)
Synonyms
GTT1
Description
StAR-related lipid transfer (START) domain containing 7 (HGNC Symbol)
Entrez gene summary
Although the function of this gene is not known, its existence is supported by mRNA and EST data. The predicted gene product contains a region similar to the STAR-related lipid transfer (START) domain, which is often present in proteins involved in the cell signaling mediated by lipid binding. Alternatively spliced transcript variants have been described, although some transcripts occur only in cancer cell lines. [provided by RefSeq, Jul 2008]
Q9NQZ5 [Direct mapping] StAR-related lipid transfer protein 7, mitochondrial
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Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0005739 [mitochondrion] GO:0008289 [lipid binding] GO:1903955 [positive regulation of protein targeting to mitochondrion]
