Expression of NKAIN1 in cancer - Summary

CANCER ATLAS

Gene description

Na+/K+ transporting ATPase interacting 1

Protein class

Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA006873

GENE INFORMATION
Gene name	NKAIN1 (HGNC Symbol)
Synonyms	FAM77C, FLJ12650
Description	Na+/K+ transporting ATPase interacting 1 (HGNC Symbol)
Entrez gene summary	NKAIN1 is a member of a family of mammalian proteins with similarity to Drosophila Nkain and interacts with the beta subunit of Na,K-ATPase (ATP1B1; MIM 182330) (Gorokhova et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009]
Chromosome	1
Cytoband	p35.2
Chromosome location (bp)	31179745 - 31239554
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000084628 (version 83.38)
Entrez gene	79570
UniProt	Q4KMZ8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q4KMZ8
Antibodypedia	NKAIN1 antibodies

PROTEIN BROWSER

NKAIN1-001	NKAIN1-002	NKAIN1-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NKAIN1-001 ENSP00000362841 ENST00000373736	Q4KMZ8 [Direct mapping] Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0002028 [regulation of sodium ion transport] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0051117 [ATPase binding] Show all	207 aa 23.6 kDa	Yes	3
NKAIN1-002 ENSP00000473611 ENST00000530145	R4GNE2 [Direct mapping] Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	126 aa 14.4 kDa	No	2
NKAIN1-004 ENSP00000433225 ENST00000526106	H0YDA0 [Direct mapping] Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	151 aa 17.1 kDa	No	2