Tissue expression of COL16A1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	COL16A1
Gene description	Collagen, type XVI, alpha 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (ovary)
GTEx:	Expressed in all
FANTOM5:	Tissue enhanced (cervix, uterine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (ovary)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cervix, uterine)

GENE INFORMATION
Gene name	COL16A1
Synonyms
Description	Collagen, type XVI, alpha 1 (HGNC Symbol)
Entrez gene summary	This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p35.2
Chromosome location (bp)	31652247 - 31704319
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000084636 (version 83.38)
Entrez gene	1307
UniProt	Q07092 (UniProt - Evidence at protein level)
neXtProt	NX_Q07092
Antibodypedia	COL16A1 antibodies

PROTEIN BROWSER

COL16A1-001	COL16A1-005	COL16A1-013	COL16A1-015	COL16A1-017

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COL16A1-001 ENSP00000362776 ENST00000373672	Q07092 [Direct mapping] Collagen alpha-1(XVI) chain Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005578 [proteinaceous extracellular matrix] GO:0005597 [collagen type XVI trimer] GO:0005788 [endoplasmic reticulum lumen] GO:0007155 [cell adhesion] GO:0007229 [integrin-mediated signaling pathway] GO:0007565 [female pregnancy] GO:0022617 [extracellular matrix disassembly] GO:0030198 [extracellular matrix organization] GO:0030574 [collagen catabolic process] GO:0033622 [integrin activation] GO:0033627 [cell adhesion mediated by integrin] GO:0051894 [positive regulation of focal adhesion assembly] GO:0071230 [cellular response to amino acid stimulus] Show all	1604 aa 157.8 kDa	Yes	0
COL16A1-005 ENSP00000362772 ENST00000373668	A6NCT7 [Direct mapping] Collagen alpha-1(XVI) chain Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		966 aa 96.8 kDa	Yes	0
COL16A1-013 ENSP00000411457 ENST00000458715	H7C3F0 [Direct mapping] Collagen alpha-1(XVI) chain Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		235 aa 22.6 kDa	No	0
COL16A1-015 ENSP00000362771 ENST00000373667	H7BY97 [Direct mapping] Collagen alpha-1(XVI) chain Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		308 aa 30.1 kDa	No	0
COL16A1-017 ENSP00000390281 ENST00000440437	H7BZL8 [Direct mapping] Collagen alpha-1(XVI) chain Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		224 aa 20.7 kDa	No	0