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Cancer tissues were negative. A single case of non Hodgkins lymphoma along with fraction of cells in a case of endometrial cancer, renal cell carcinoma and melanoma displayed moderate cytoplasmic positivity.
GENE INFORMATION
Gene name
HBQ1 (HGNC Symbol)
Synonyms
HBQ
Description
Hemoglobin, theta 1 (HGNC Symbol)
Entrez gene summary
Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue. [provided by RefSeq, Jul 2008]
