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RBM22

GENERAL INFORMATION

Gene name

 RBM22

Gene description

 RNA binding motif protein 22

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA001634
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RBM22 (HGNC Symbol)

Synonyms

 Cwc2, FLJ10290, fSAP47, ZC3H16

Description

 RNA binding motif protein 22 (HGNC Symbol)

Entrez gene summary

 This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009]

Chromosome

 5

Cytoband

 q33.1

Chromosome location (bp)

 150690794 - 150701107

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000086589 (version 83.38)

Entrez gene

 55696

UniProt

 Q9NW64 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NW64

Antibodypedia

 RBM22 antibodies

PROTEIN BROWSER
RBM22-001
RBM22-002
RBM22-007
RBM22-009

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RBM22-001
ENSP00000199814
ENST00000199814
Q9NW64 [Direct mapping]
Pre-mRNA-splicing factor RBM22
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000060 [protein import into nucleus, translocation]
GO:0000166 [nucleotide binding]
GO:0000387 [spliceosomal snRNP assembly]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0000974 [Prp19 complex]
GO:0003676 [nucleic acid binding]
GO:0005487 [nucleocytoplasmic transporter activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0017070 [U6 snRNA binding]
GO:0033120 [positive regulation of RNA splicing]
GO:0035690 [cellular response to drug]
GO:0036002 [pre-mRNA binding]
GO:0044822 [poly(A) RNA binding]
GO:0045292 [mRNA cis splicing, via spliceosome]
GO:0046872 [metal ion binding]
GO:0048306 [calcium-dependent protein binding]
GO:0071006 [U2-type catalytic step 1 spliceosome]
GO:0071007 [U2-type catalytic step 2 spliceosome]
GO:0071013 [catalytic step 2 spliceosome]
GO:0090316 [positive regulation of intracellular protein transport]
Show all
 420 aa
46.9 kDa 		No 0
RBM22-002
ENSP00000412118
ENST00000447771
Q9NW64 [Direct mapping]
Pre-mRNA-splicing factor RBM22
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000060 [protein import into nucleus, translocation]
GO:0000166 [nucleotide binding]
GO:0000387 [spliceosomal snRNP assembly]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0000974 [Prp19 complex]
GO:0003676 [nucleic acid binding]
GO:0005487 [nucleocytoplasmic transporter activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0017070 [U6 snRNA binding]
GO:0033120 [positive regulation of RNA splicing]
GO:0035690 [cellular response to drug]
GO:0036002 [pre-mRNA binding]
GO:0044822 [poly(A) RNA binding]
GO:0045292 [mRNA cis splicing, via spliceosome]
GO:0046872 [metal ion binding]
GO:0048306 [calcium-dependent protein binding]
GO:0071006 [U2-type catalytic step 1 spliceosome]
GO:0071007 [U2-type catalytic step 2 spliceosome]
GO:0071013 [catalytic step 2 spliceosome]
GO:0090316 [positive regulation of intracellular protein transport]
Show all
 371 aa
41.2 kDa 		No 0
RBM22-007
ENSP00000430946
ENST00000521464
E5RHA8 [Direct mapping]
Pre-mRNA-splicing factor RBM22
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 243 aa
26.7 kDa 		No 0
RBM22-009
ENSP00000428154
ENST00000518917
E5RJW4 [Direct mapping]
Pre-mRNA-splicing factor RBM22
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0046872 [metal ion binding]
Show all
 179 aa
20.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.