Expression of PGS1 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Phosphatidylglycerophosphate synthase 1

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA022526

GENE INFORMATION
Gene name	PGS1 (HGNC Symbol)
Synonyms	DKFZP762M186
Description	Phosphatidylglycerophosphate synthase 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.3
Chromosome location (bp)	78378640 - 78425114
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000087157 (version 83.38)
Entrez gene	9489
UniProt	Q32NB8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q32NB8
Antibodypedia	PGS1 antibodies

PROTEIN BROWSER

PGS1-001	PGS1-003	PGS1-006	PGS1-010	PGS1-011	PGS1-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PGS1-001 ENSP00000262764 ENST00000262764	Q32NB8 [Direct mapping] CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial A0A024R8V5 [Target identity:100%; Query identity:100%] HCG1642326, isoform CRA_b Show all	Enzymes ENZYME proteins Transferases Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005509 [calcium ion binding] GO:0005524 [ATP binding] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005783 [endoplasmic reticulum] GO:0006644 [phospholipid metabolic process] GO:0006655 [phosphatidylglycerol biosynthetic process] GO:0008444 [CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity] GO:0008654 [phospholipid biosynthetic process] GO:0016780 [phosphotransferase activity, for other substituted phosphate groups] GO:0032049 [cardiolipin biosynthetic process] GO:0044281 [small molecule metabolic process] GO:0046339 [diacylglycerol metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] Show all	556 aa 62.7 kDa	No	0
PGS1-003 ENSP00000465908 ENST00000589689	K7EL44 [Direct mapping] CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008654 [phospholipid biosynthetic process] GO:0016780 [phosphotransferase activity, for other substituted phosphate groups] Show all	384 aa 43.3 kDa	No	0
PGS1-006 ENSP00000466219 ENST00000592043	K7ELT9 [Direct mapping] CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008654 [phospholipid biosynthetic process] GO:0016780 [phosphotransferase activity, for other substituted phosphate groups] Show all	330 aa 37 kDa	No	0
PGS1-010 ENSP00000467569 ENST00000586019	K7EPX0 [Direct mapping] CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008654 [phospholipid biosynthetic process] GO:0016780 [phosphotransferase activity, for other substituted phosphate groups] Show all	132 aa 14.5 kDa	No	0
PGS1-011 ENSP00000467719 ENST00000586355	K7EQ89 [Direct mapping] CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		114 aa 11.4 kDa	No	0
PGS1-014 ENSP00000465266 ENST00000587356	K7EJP6 [Direct mapping] CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008654 [phospholipid biosynthetic process] GO:0016780 [phosphotransferase activity, for other substituted phosphate groups] Show all	264 aa 29.6 kDa	No	0