Cell atlas - OGFOD1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

OGFOD1

TISSUE

premium

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleus

Human cell
	Cytosol
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	OGFOD1
Gene description	2-oxoglutarate and iron-dependent oxygenase domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleus. In addition localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (supported)
Additional location	In addition localized to the Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA003215
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleus. In addition localized to the cytosol.

Main location

Nucleus (supported)

Additional location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA003215	A-431	Nucleus
	HPA003215	A-431	Cytosol
	HPA003215	U-2 OS	Nucleus
	HPA003215	U-2 OS	Cytosol
	HPA003215	U-251 MG	Nucleus
	HPA003215	U-251 MG	Cytosol

GENE INFORMATION
Gene name	OGFOD1 (HGNC Symbol)
Synonyms	FLJ10826, KIAA1612, TPA1
Description	2-oxoglutarate and iron-dependent oxygenase domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q13
Chromosome location (bp)	56451490 - 56479100
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000087263 (version 83.38)
Entrez gene	55239
UniProt	Q8N543 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N543
Antibodypedia	OGFOD1 antibodies

PROTEIN BROWSER

OGFOD1-001	OGFOD1-003	OGFOD1-009	OGFOD1-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OGFOD1-001 ENSP00000457258 ENST00000566157	Q8N543 [Direct mapping] Prolyl 3-hydroxylase OGFOD1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006449 [regulation of translational termination] GO:0008283 [cell proliferation] GO:0010494 [cytoplasmic stress granule] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0016706 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors] GO:0018126 [protein hydroxylation] GO:0019511 [peptidyl-proline hydroxylation] GO:0031418 [L-ascorbic acid binding] GO:0031543 [peptidyl-proline dioxygenase activity] GO:0031544 [peptidyl-proline 3-dioxygenase activity] GO:0034063 [stress granule assembly] GO:0055114 [oxidation-reduction process] Show all	542 aa 63.2 kDa	No	0
OGFOD1-003 ENSP00000457746 ENST00000568397	A0A0A0MTR2 [Direct mapping] Prolyl 3-hydroxylase OGFOD1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0016706 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors] GO:0031418 [L-ascorbic acid binding] GO:0055114 [oxidation-reduction process] Show all	499 aa 58.4 kDa	No	0
OGFOD1-009 ENSP00000457553 ENST00000561646	H3BUA6 [Direct mapping] Prolyl 3-hydroxylase OGFOD1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0055114 [oxidation-reduction process] Show all	175 aa 20.8 kDa	No	0
OGFOD1-011 ENSP00000456111 ENST00000562150	H3BR79 [Direct mapping] Prolyl 3-hydroxylase OGFOD1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		164 aa 19.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.