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TESC

CANCER ATLAS

Gene description

 Tescalcin

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA053200

GENE INFORMATION

Gene name

 TESC (HGNC Symbol)

Synonyms

 CHP3, FLJ20607, TSC

Description

 Tescalcin (HGNC Symbol)

Entrez gene summary

Chromosome

 12

Cytoband

 q24.22

Chromosome location (bp)

 117038923 - 117099479

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000088992 (version 83.38)

Entrez gene

 54997

UniProt

 Q96BS2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96BS2

Antibodypedia

 TESC antibodies

PROTEIN BROWSER
TESC-001
TESC-007
TESC-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TESC-001
ENSP00000334785
ENST00000335209
Q96BS2 [Direct mapping]
Calcineurin B homologous protein 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0001726 [ruffle]
GO:0004860 [protein kinase inhibitor activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0008285 [negative regulation of cell proliferation]
GO:0008584 [male gonad development]
GO:0010628 [positive regulation of gene expression]
GO:0019212 [phosphatase inhibitor activity]
GO:0030027 [lamellipodium]
GO:0030219 [megakaryocyte differentiation]
GO:0030854 [positive regulation of granulocyte differentiation]
GO:0032417 [positive regulation of sodium:proton antiporter activity]
GO:0032587 [ruffle membrane]
GO:0033628 [regulation of cell adhesion mediated by integrin]
GO:0042803 [protein homodimerization activity]
GO:0043086 [negative regulation of catalytic activity]
GO:0045654 [positive regulation of megakaryocyte differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0050821 [protein stabilization]
GO:0051604 [protein maturation]
GO:0071300 [cellular response to retinoic acid]
GO:0072661 [protein targeting to plasma membrane]
GO:1904030 [negative regulation of cyclin-dependent protein kinase activity]
Show all
 214 aa
24.7 kDa 		No 0
TESC-007
ENSP00000450386
ENST00000549210
H0YIX4 [Direct mapping]
Calcineurin B homologous protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 81 aa
9.1 kDa 		No 0
TESC-201
ENSP00000445689
ENST00000541210
Q96BS2 [Direct mapping]
Calcineurin B homologous protein 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0001726 [ruffle]
GO:0004860 [protein kinase inhibitor activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0008285 [negative regulation of cell proliferation]
GO:0010628 [positive regulation of gene expression]
GO:0019212 [phosphatase inhibitor activity]
GO:0030027 [lamellipodium]
GO:0030854 [positive regulation of granulocyte differentiation]
GO:0032417 [positive regulation of sodium:proton antiporter activity]
GO:0032587 [ruffle membrane]
GO:0033628 [regulation of cell adhesion mediated by integrin]
GO:0042803 [protein homodimerization activity]
GO:0045654 [positive regulation of megakaryocyte differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0050821 [protein stabilization]
GO:0051604 [protein maturation]
GO:0071300 [cellular response to retinoic acid]
GO:0072661 [protein targeting to plasma membrane]
GO:1904030 [negative regulation of cyclin-dependent protein kinase activity]
Show all
 187 aa
21.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.