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DTX2

CANCER ATLAS

Gene description

 Deltex 2, E3 ubiquitin ligase

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA042931

GENE INFORMATION

Gene name

 DTX2 (HGNC Symbol)

Synonyms

 KIAA1528, RNF58

Description

 Deltex 2, E3 ubiquitin ligase (HGNC Symbol)

Entrez gene summary

 DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009]

Chromosome

 7

Cytoband

 q11.23

Chromosome location (bp)

 76461676 - 76505995

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000091073 (version 83.38)

Entrez gene

 113878

UniProt

 Q86UW9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q86UW9

Antibodypedia

 DTX2 antibodies

PROTEIN BROWSER
«
DTX2-001
DTX2-002
DTX2-003
DTX2-004
DTX2-005
DTX2-009
DTX2-010
DTX2-011
DTX2-012
DTX2-015
DTX2-016
DTX2-017
DTX2-019
DTX2-021
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DTX2-001
ENSP00000322885
ENST00000324432
Q86UW9 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0031965 [nuclear membrane]
GO:0046872 [metal ion binding]
Show all
 622 aa
67.2 kDa 		No 0
DTX2-002
ENSP00000397648
ENST00000446600
E7ET89 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0008270 [zinc ion binding]
GO:0031965 [nuclear membrane]
GO:0046872 [metal ion binding]
Show all
 531 aa
57.3 kDa 		No 0
DTX2-003
ENSP00000390218
ENST00000413936
Q86UW9 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0031965 [nuclear membrane]
GO:0046872 [metal ion binding]
Show all
 622 aa
67.2 kDa 		No 0
DTX2-004
ENSP00000411986
ENST00000430490
Q86UW9 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0031965 [nuclear membrane]
GO:0046872 [metal ion binding]
Show all
 622 aa
67.2 kDa 		No 0
DTX2-005
ENSP00000392545
ENST00000446820
Q86UW9 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0031965 [nuclear membrane]
GO:0046872 [metal ion binding]
Show all
 575 aa
62.3 kDa 		No 0
DTX2-009
ENSP00000392114
ENST00000442516
C9IYX1 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 14 aa
1.5 kDa 		No 0
DTX2-010
ENSP00000407398
ENST00000425780
C9JVC8 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 65 aa
7.1 kDa 		No 0
DTX2-011
ENSP00000409040
ENST00000456590
C9JLU8 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 25 aa
2.7 kDa 		No 0
DTX2-012
ENSP00000389231
ENST00000451769
C9JS11 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 28 aa
3 kDa 		No 0
DTX2-015
ENSP00000390881
ENST00000457529
C9JF39 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 62 aa
6.8 kDa 		No 0
DTX2-016
ENSP00000415838
ENST00000423646
C9JII1 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
Show all
 140 aa
15.6 kDa 		No 0
DTX2-017
ENSP00000387894
ENST00000438930
C9JY61 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
Show all
 90 aa
9.9 kDa 		No 0
DTX2-019
ENSP00000403342
ENST00000429179
C9JEH4 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
Show all
 108 aa
12 kDa 		No 0
DTX2-021
ENSP00000399639
ENST00000435861
C9JY61 [Direct mapping]
Probable E3 ubiquitin-protein ligase DTX2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008270 [zinc ion binding]
Show all
 90 aa
9.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.