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SCFD1

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GENERAL INFORMATION

Gene name

 SCFD1

Gene description

 Sec1 family domain containing 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the nucleoplasm. In addition localized to the cytosol.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoplasm (approved)

Additional location

 In addition localized to the Cytosol (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA003579
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

 Nucleoplasm (approved)

Additional location

 Cytosol (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA003579 A-431 Nucleoplasm
Cytosol
HPA003579 U-251 MG Nucleoplasm
Cytosol

GENE INFORMATION

Gene name

 SCFD1 (HGNC Symbol)

Synonyms

 C14orf163, KIAA0917, RA410, SLY1, STXBP1L2

Description

 Sec1 family domain containing 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 14

Cytoband

 q12

Chromosome location (bp)

 30622112 - 30735812

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000092108 (version 83.38)

Entrez gene

 23256

UniProt

 Q8WVM8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WVM8

Antibodypedia

 SCFD1 antibodies

PROTEIN BROWSER
SCFD1-001
SCFD1-004
SCFD1-006
SCFD1-010
SCFD1-014
SCFD1-015

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SCFD1-001
ENSP00000452448
ENST00000469043
H0YJY1 [Direct mapping]
Sec1 family domain-containing protein 1
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005623 [cell]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0016192 [vesicle-mediated transport]
Show all
 144 aa
16.6 kDa 		No 0
SCFD1-004
ENSP00000443010
ENST00000544052
Q8WVM8 [Direct mapping]
Sec1 family domain-containing protein 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000902 [cell morphogenesis]
GO:0005515 [protein binding]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005798 [Golgi-associated vesicle]
GO:0005801 [cis-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006892 [post-Golgi vesicle-mediated transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006909 [phagocytosis]
GO:0009636 [response to toxic substance]
GO:0015031 [protein transport]
GO:0016192 [vesicle-mediated transport]
GO:0017119 [Golgi transport complex]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0019905 [syntaxin binding]
GO:0031201 [SNARE complex]
GO:0032580 [Golgi cisterna membrane]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0051223 [regulation of protein transport]
GO:0060628 [regulation of ER to Golgi vesicle-mediated transport]
GO:0061024 [membrane organization]
GO:1902902 [negative regulation of autophagosome assembly]
Show all
 575 aa
65.1 kDa 		No 0
SCFD1-006
ENSP00000390783
ENST00000458591
Q8WVM8 [Direct mapping]
Sec1 family domain-containing protein 1
Show all
   THUMBUP predicted membrane proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000902 [cell morphogenesis]
GO:0001666 [response to hypoxia]
GO:0005515 [protein binding]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005798 [Golgi-associated vesicle]
GO:0005801 [cis-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006892 [post-Golgi vesicle-mediated transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006909 [phagocytosis]
GO:0009636 [response to toxic substance]
GO:0015031 [protein transport]
GO:0016192 [vesicle-mediated transport]
GO:0017119 [Golgi transport complex]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0019905 [syntaxin binding]
GO:0031201 [SNARE complex]
GO:0032580 [Golgi cisterna membrane]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0047485 [protein N-terminus binding]
GO:0048208 [COPII vesicle coating]
GO:0051223 [regulation of protein transport]
GO:0060628 [regulation of ER to Golgi vesicle-mediated transport]
GO:0061024 [membrane organization]
GO:1901998 [toxin transport]
GO:1902902 [negative regulation of autophagosome assembly]
Show all
 642 aa
72.4 kDa 		No 0
SCFD1-010
ENSP00000379870
ENST00000396629
Q8WVM8 [Direct mapping]
Sec1 family domain-containing protein 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000902 [cell morphogenesis]
GO:0005515 [protein binding]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005798 [Golgi-associated vesicle]
GO:0005801 [cis-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006892 [post-Golgi vesicle-mediated transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006909 [phagocytosis]
GO:0009636 [response to toxic substance]
GO:0015031 [protein transport]
GO:0016192 [vesicle-mediated transport]
GO:0017119 [Golgi transport complex]
GO:0018279 [protein N-linked glycosylation via asparagine]
GO:0019905 [syntaxin binding]
GO:0031201 [SNARE complex]
GO:0032580 [Golgi cisterna membrane]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0048208 [COPII vesicle coating]
GO:0051223 [regulation of protein transport]
GO:0060628 [regulation of ER to Golgi vesicle-mediated transport]
GO:0061024 [membrane organization]
GO:1902902 [negative regulation of autophagosome assembly]
Show all
 550 aa
62.3 kDa 		No 0
SCFD1-014
ENSP00000450755
ENST00000557076
G3V2M8 [Direct mapping]
Sec1 family domain-containing protein 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005623 [cell]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0016192 [vesicle-mediated transport]
Show all
 198 aa
22.5 kDa 		No 0
SCFD1-015
ENSP00000452308
ENST00000553693
G3V5E2 [Direct mapping]
Sec1 family domain-containing protein 1
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005623 [cell]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0016192 [vesicle-mediated transport]
Show all
 84 aa
9.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.