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A majority of the few positive cancer tissues showed weak to moderate cytoplasmic staining. Strongest positivity in squamous cell carcinomas. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
TYRO3 (HGNC Symbol)
Synonyms
Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif
Description
TYRO3 protein tyrosine kinase (HGNC Symbol)
Entrez gene summary
The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]