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Gene name

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Chromosome

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In atlas

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Reliability

Reliability

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Validation

Method

Validation

Method

Validation

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Searches

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Detectable

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KRT31
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

KRT31

Gene description

Keratin 31, type I

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Group enriched (skin, esophagus)
GTEx:Tissue enhanced (skin)
FANTOM5:Group enriched (cerebellum, esophagus)

Protein evidence

Evidence at protein level

Protein expression

Highly expressed in hair follicle cortex.

DATA RELIABILITY

Data reliability
description

Caution, targets protein from more than one gene. Pending external verification. Protein expression in hair follicles can be correlated with GTEx RNA data.

Reliability score

Supported based on 2 antibodies.
HPA049550 , HPA055194
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Hair
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Hair

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (skin, esophagus)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (skin)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (cerebellum, esophagus)

GENE INFORMATION

Gene name

KRT31 (HGNC Symbol)

Synonyms

Ha-1, KRTHA1

Description

Keratin 31, type I (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.2

Chromosome location (bp)

41393724 - 41397592

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000094796 (version 83.38)

Entrez gene

3881

UniProt

Q15323 (UniProt - Evidence at protein level)

neXtProt

NX_Q15323

Antibodypedia

KRT31 antibodies

PROTEIN BROWSER

KRT31-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KRT31-001
ENSP00000251645
ENST00000251645
Q15323 [Direct mapping]
Keratin, type I cuticular Ha1
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005198 [structural molecule activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005882 [intermediate filament]
GO:0008544 [epidermis development]
GO:0070062 [extracellular exosome]
Show all
416 aa
47.2 kDa
No 0

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