Expression of ARCN1 in cancer - Summary

CANCER ATLAS

Gene description

Archain 1

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA037573

GENE INFORMATION
Gene name	ARCN1 (HGNC Symbol)
Synonyms	COPD
Description	Archain 1 (HGNC Symbol)
Entrez gene summary	This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q23.3
Chromosome location (bp)	118572390 - 118603033
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000095139 (version 83.38)
Entrez gene	372
UniProt	P48444 (UniProt - Evidence at protein level)
neXtProt	NX_P48444
Antibodypedia	ARCN1 antibodies

PROTEIN BROWSER

ARCN1-001	ARCN1-002	ARCN1-003	ARCN1-004	ARCN1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARCN1-001 ENSP00000264028 ENST00000264028	P48444 [Direct mapping] Coatomer subunit delta B0YIW5 [Target identity:100%; Query identity:100%] Archain 1, isoform CRA_b; Coatomer subunit delta variant 1; cDNA, FLJ92603, Homo sapiens archain 1 (ARCN1), mRNA Show all	Phobius predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005829 [cytosol] GO:0006810 [transport] GO:0006886 [intracellular protein transport] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0008344 [adult locomotory behavior] GO:0016020 [membrane] GO:0021691 [cerebellar Purkinje cell layer maturation] GO:0030126 [COPI vesicle coat] GO:0030137 [COPI-coated vesicle] GO:0043231 [intracellular membrane-bounded organelle] GO:0043473 [pigmentation] GO:0044822 [poly(A) RNA binding] GO:0048193 [Golgi vesicle transport] GO:0048205 [COPI coating of Golgi vesicle] GO:0061024 [membrane organization] Show all	511 aa 57.2 kDa	No	0
ARCN1-002 ENSP00000431676 ENST00000534182	E9PK34 [Direct mapping] Coatomer subunit delta Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] Show all	83 aa 9.1 kDa	Yes	0
ARCN1-003 ENSP00000352385 ENST00000359415	B0YIW6 [Direct mapping] Archain 1, isoform CRA_a; Coatomer subunit delta; Coatomer subunit delta variant 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0006810 [transport] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0043231 [intracellular membrane-bounded organelle] Show all	552 aa 61.6 kDa	No	0
ARCN1-004 ENSP00000376599 ENST00000392859	P48444 [Direct mapping] Coatomer subunit delta Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0005829 [cytosol] GO:0006810 [transport] GO:0006886 [intracellular protein transport] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0016020 [membrane] GO:0030126 [COPI vesicle coat] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] GO:0048205 [COPI coating of Golgi vesicle] GO:0061024 [membrane organization] Show all	423 aa 47.2 kDa	No	0
ARCN1-201 ENSP00000482114 ENST00000614498	Q6P1Q5 [Direct mapping] ARCN1 protein; Coatomer subunit delta Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0015031 [protein transport] Show all	189 aa 21.9 kDa	No	0