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CREM

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GENERAL INFORMATION

Gene name

 CREM

Gene description

 CAMP responsive element modulator

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 34
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the nucleus. In addition localized to vesicles.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleus (supported)

Additional location

 In addition localized to the Vesicles (approved)

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
CAB018352
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the nucleus. In addition localized to vesicles.

Main location

 Nucleus (supported)

Additional location

 Vesicles (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
CAB018352 A-431 Nucleus
Vesicles
CAB018352 U-2 OS Nucleus
CAB018352 U-251 MG Nucleoplasm

GENE INFORMATION

Gene name

 CREM (HGNC Symbol)

Synonyms

 hCREM-2

Description

 CAMP responsive element modulator (HGNC Symbol)

Entrez gene summary

 This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]

Chromosome

 10

Cytoband

 p11.21

Chromosome location (bp)

 35126791 - 35212958

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000095794 (version 83.38)

Entrez gene

 1390

UniProt

 Q03060 (UniProt - Evidence at protein level)

neXtProt

 NX_Q03060

Antibodypedia

 CREM antibodies

PROTEIN BROWSER
«
CREM-001
CREM-002
CREM-003
CREM-004
CREM-006
CREM-007
CREM-008
CREM-009
CREM-010
CREM-012
CREM-014
CREM-016
CREM-017
CREM-018
CREM-021
CREM-023
CREM-026
CREM-027
CREM-028
CREM-029
CREM-032
CREM-034
CREM-045
CREM-047
CREM-048
CREM-049
CREM-052
CREM-053
CREM-054
CREM-055
CREM-056
CREM-057
CREM-201
CREM-202
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CREM-001
ENSP00000265372
ENST00000345491
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001046 [core promoter sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0006006 [glucose metabolic process]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006631 [fatty acid metabolic process]
GO:0006687 [glycosphingolipid metabolic process]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0007623 [circadian rhythm]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0032922 [circadian regulation of gene expression]
GO:0042752 [regulation of circadian rhythm]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0051591 [response to cAMP]
Show all
 300 aa
32.5 kDa 		No 0
CREM-002
ENSP00000363858
ENST00000374726
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
Show all
 137 aa
14.9 kDa 		No 0
CREM-003
ENSP00000420681
ENST00000473940
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 120 aa
13.4 kDa 		No 0
CREM-004
ENSP00000417460
ENST00000488328
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 109 aa
12.2 kDa 		No 0
CREM-006
ENSP00000349387
ENST00000356917
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 108 aa
12.1 kDa 		No 0
CREM-007
ENSP00000417562
ENST00000474931
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 112 aa
12.7 kDa 		No 0
CREM-008
ENSP00000344365
ENST00000344351
E9PAR2 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 95 aa
10.9 kDa 		No 0
CREM-009
ENSP00000419075
ENST00000488741
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 102 aa
11.5 kDa 		No 0
CREM-010
ENSP00000417327
ENST00000490511
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 113 aa
12.7 kDa 		No 0
CREM-012
ENSP00000341875
ENST00000342105
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 245 aa
26.5 kDa 		No 0
CREM-014
ENSP00000354593
ENST00000361599
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 270 aa
29.7 kDa 		No 0
CREM-016
ENSP00000419018
ENST00000474362
E9PB41 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 96 aa
11 kDa 		No 0
CREM-017
ENSP00000420437
ENST00000460270
E9PAR2 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 95 aa
10.9 kDa 		No 0
CREM-018
ENSP00000346804
ENST00000354759
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 248 aa
27.5 kDa 		No 0
CREM-021
ENSP00000345384
ENST00000348787
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 221 aa
24.4 kDa 		No 0
CREM-023
ENSP00000393538
ENST00000429130
J3KQC0 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 345 aa
37 kDa 		No 0
CREM-026
ENSP00000417807
ENST00000487763
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 121 aa
13.5 kDa 		No 0
CREM-027
ENSP00000417165
ENST00000484283
J3KR46 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 219 aa
24.7 kDa 		No 0
CREM-028
ENSP00000419684
ENST00000463960
C9K092 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 193 aa
21.5 kDa 		No 0
CREM-029
ENSP00000420511
ENST00000479070
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 312 aa
33.8 kDa 		No 0
CREM-032
ENSP00000363853
ENST00000374721
G5E998 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 269 aa
29.4 kDa 		No 0
CREM-034
ENSP00000379225
ENST00000395887
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 282 aa
31 kDa 		No 0
CREM-045
ENSP00000473519
ENST00000469949
R4GN75 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 59 aa
6.3 kDa 		No 0
CREM-047
ENSP00000419924
ENST00000489321
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
Show all
 137 aa
14.9 kDa 		No 0
CREM-048
ENSP00000403938
ENST00000427847
A0A0A0MSU8 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 157 aa
16.9 kDa 		No 0
CREM-049
ENSP00000418798
ENST00000487132
C9IYM9 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 187 aa
20.5 kDa 		No 0
CREM-052
ENSP00000417399
ENST00000494479
C9J2J0 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 116 aa
11.7 kDa 		No 0
CREM-053
ENSP00000418336
ENST00000463314
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 138 aa
15.1 kDa 		No 0
CREM-054
ENSP00000419810
ENST00000468236
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 125 aa
14 kDa 		No 0
CREM-055
ENSP00000417130
ENST00000495301
C9J5A7 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 78 aa
7.9 kDa 		No 0
CREM-056
ENSP00000337138
ENST00000337656
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 299 aa
32.5 kDa 		No 0
CREM-057
ENSP00000363866
ENST00000374734
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 236 aa
26.3 kDa 		No 0
CREM-201
ENSP00000363860
ENST00000374728
Q03060 [Direct mapping]
cAMP-responsive element modulator
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Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 221 aa
24.4 kDa 		No 0
CREM-202
ENSP00000409220
ENST00000439705
Q03060 [Direct mapping]
cAMP-responsive element modulator
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008140 [cAMP response element binding protein binding]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 248 aa
27.5 kDa 		No 0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.