Expression of CRISP3 in cancer - Summary

CANCER ATLAS

Gene description

Cysteine-rich secretory protein 3

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA054392

GENE INFORMATION
Gene name	CRISP3 (HGNC Symbol)
Synonyms	Aeg2, CRISP-3, CRS3, dJ442L6.3, SGP28
Description	Cysteine-rich secretory protein 3 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p12.3
Chromosome location (bp)	49727384 - 49744437
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000096006 (version 83.38)
Entrez gene	10321
UniProt	P54108 (UniProt - Evidence at protein level)
neXtProt	NX_P54108
Antibodypedia	CRISP3 antibodies

PROTEIN BROWSER

CRISP3-001	CRISP3-002	CRISP3-003	CRISP3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CRISP3-001 ENSP00000263045 ENST00000263045	P54108 [Direct mapping] Cysteine-rich secretory protein 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005576 [extracellular region] GO:0005578 [proteinaceous extracellular matrix] GO:0005615 [extracellular space] GO:0006952 [defense response] GO:0042581 [specific granule] GO:0045087 [innate immune response] GO:0070062 [extracellular exosome] Show all	258 aa 29.1 kDa	Yes	0
CRISP3-002 ENSP00000346636 ENST00000354620	I3L0A1 [Direct mapping] Cysteine-rich secretory protein 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0016021 [integral component of membrane] Show all	191 aa 21.6 kDa	No	0
CRISP3-003 ENSP00000360201 ENST00000371159	J3KPA1 [Direct mapping] Cysteine-rich secretory protein 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0016021 [integral component of membrane] Show all	276 aa 31 kDa	No	0
CRISP3-201 ENSP00000389026 ENST00000433368	P54108 [Direct mapping] Cysteine-rich secretory protein 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005576 [extracellular region] GO:0005578 [proteinaceous extracellular matrix] GO:0005615 [extracellular space] GO:0006952 [defense response] GO:0042581 [specific granule] GO:0045087 [innate immune response] GO:0070062 [extracellular exosome] Show all	268 aa 30.1 kDa	No	0