Tissue expression of AMELY - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	AMELY
Gene description	Amelogenin, Y-linked
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Not detected
GTEx:	Not detected

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Not detected
GTEx dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	AMELY (HGNC Symbol)
Synonyms	AMGL
Description	Amelogenin, Y-linked (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. [provided by RefSeq, Jul 2008]
Chromosome	Y
Cytoband	p11.2
Chromosome location (bp)	6865918 - 6874027
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000099721 (version 83.38)
Entrez gene	266
UniProt	Q99218 (UniProt - Evidence at transcript level)
neXtProt	NX_Q99218
Antibodypedia	AMELY antibodies

PROTEIN BROWSER

AMELY-001	AMELY-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AMELY-001 ENSP00000215479 ENST00000215479	Q99218 [Direct mapping] Amelogenin, Y isoform Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005578 [proteinaceous extracellular matrix] GO:0007275 [multicellular organismal development] GO:0030345 [structural constituent of tooth enamel] GO:0031012 [extracellular matrix] GO:0031214 [biomineral tissue development] Show all	192 aa 21.7 kDa	Yes	0
AMELY-002 ENSP00000372505 ENST00000383036	Q99218 [Direct mapping] Amelogenin, Y isoform Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005578 [proteinaceous extracellular matrix] GO:0007275 [multicellular organismal development] GO:0030345 [structural constituent of tooth enamel] GO:0031012 [extracellular matrix] GO:0031214 [biomineral tissue development] Show all	206 aa 23.2 kDa	Yes	0