Expression of IZUMO4 in cancer - Summary

CANCER ATLAS

Gene description

IZUMO family member 4

Protein class

Predicted intracellular proteins, Predicted secreted proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Testis cancer

STAINING SUMMARY

HPA045099	HPA048496

GENE INFORMATION
Gene name	IZUMO4 (HGNC Symbol)
Synonyms	C19orf36
Description	IZUMO family member 4 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	2096429 - 2099593
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000099840 (version 83.38)
Entrez gene	113177
UniProt	Q1ZYL8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q1ZYL8
Antibodypedia	IZUMO4 antibodies

PROTEIN BROWSER

IZUMO4-001	IZUMO4-004	IZUMO4-005	IZUMO4-009	IZUMO4-010	IZUMO4-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IZUMO4-001 ENSP00000378718 ENST00000395307	Q1ZYL8 [Direct mapping] Izumo sperm-egg fusion protein 4 Show all	Transporters Accessory Factors Involved in Transport Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0005576 [extracellular region] GO:0005634 [nucleus] Show all	214 aa 24.5 kDa	Yes	0
IZUMO4-004 ENSP00000378712 ENST00000395301	Q1ZYL8 [Direct mapping] Izumo sperm-egg fusion protein 4 Show all	Transporters Accessory Factors Involved in Transport Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0005576 [extracellular region] GO:0005634 [nucleus] Show all	232 aa 26.5 kDa	Yes	0
IZUMO4-005 ENSP00000484309 ENST00000620263	A0A087X1M1 [Direct mapping] Izumo sperm-egg fusion protein 4 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		184 aa 20.9 kDa	Yes	0
IZUMO4-009 ENSP00000484639 ENST00000588003	A0A087X221 [Direct mapping] Izumo sperm-egg fusion protein 4 Show all	Predicted intracellular proteins Show all		152 aa 16.5 kDa	No	0
IZUMO4-010 ENSP00000378709 ENST00000395296	A0A0A0MS61 [Direct mapping] Izumo sperm-egg fusion protein 4 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		208 aa 23.8 kDa	Yes	0
IZUMO4-013 ENSP00000483922 ENST00000610800	A0A087X160 [Direct mapping] Izumo sperm-egg fusion protein 4 Show all	Predicted intracellular proteins Show all		152 aa 17.4 kDa	No	0