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Few adenocarcinomas of lung showed moderate to strong cytoplasmic staining. Weak to moderate cytoplasmic immunoreactivity was observed in a few cases of stomach and pancreatic cancers. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
SEC14L3 (HGNC Symbol)
Synonyms
TAP2
Description
SEC14-like lipid binding 3 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thus is required for the export of yeast secretory proteins from the Golgi complex. The specific function of this protein has not yet been determined. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]