Cell atlas - ANKRD54 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ANKRD54

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS CELL CYCLE

GENE/PROTEIN

Antibody validation

Dictionary
	Microtubules
	Midbody
	Nucleoplasm

Human cell
	Microtubules
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	ANKRD54
Gene description	Ankyrin repeat domain 54
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the microtubules & midbody. In addition localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Microtubules (approved), Midbody (approved)
Additional location	In addition localized to the Nucleoplasm (approved)
Single-cell variation	Single-cell variation in protein expression observed.
Cell cycle dependency	Cell cycle dependent expression determined by biological definition

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA071287
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the microtubules & midbody. In addition localized to the nucleoplasm.

Main location

Microtubules (approved), Midbody (approved)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA071287	HEK 293	Midbody	Intensity	Intensity
	HPA071287	SK-MEL-30	Nucleoplasm
	HPA071287	SK-MEL-30	Microtubules
	HPA071287	U-2 OS	Nucleoplasm
	HPA071287	U-2 OS	Microtubules

CELL CYCLE
Summary	Expression has cell cycle dependency according to biological definition

GENE INFORMATION
Gene name	ANKRD54 (HGNC Symbol)
Synonyms	LIAR
Description	Ankyrin repeat domain 54 (HGNC Symbol)
Entrez gene summary
Chromosome	22
Cytoband	q13.1
Chromosome location (bp)	37830855 - 37849327
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100124 (version 83.38)
Entrez gene	129138
UniProt	Q6NXT1 (UniProt - Evidence at protein level)
neXtProt	NX_Q6NXT1
Antibodypedia	ANKRD54 antibodies

PROTEIN BROWSER

ANKRD54-001	ANKRD54-003	ANKRD54-004	ANKRD54-005	ANKRD54-006	ANKRD54-010	ANKRD54-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANKRD54-001 ENSP00000215941 ENST00000215941	Q6NXT1 [Direct mapping] Ankyrin repeat domain-containing protein 54 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006913 [nucleocytoplasmic transport] GO:0019887 [protein kinase regulator activity] GO:0030496 [midbody] GO:0032403 [protein complex binding] GO:0045648 [positive regulation of erythrocyte differentiation] GO:0045859 [regulation of protein kinase activity] GO:1902531 [regulation of intracellular signal transduction] Show all	300 aa 32.5 kDa	No	0
ANKRD54-003 ENSP00000393035 ENST00000424350	C9JX82 [Direct mapping] Ankyrin repeat domain-containing protein 54 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	90 aa 9.8 kDa	No	0
ANKRD54-004 ENSP00000405782 ENST00000411961	D3YTC9 [Direct mapping] Ankyrin repeat domain-containing protein 54 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	284 aa 30.8 kDa	No	0
ANKRD54-005 ENSP00000387507 ENST00000434930	C9JU48 [Direct mapping] Ankyrin repeat domain-containing protein 54 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	217 aa 22.7 kDa	No	0
ANKRD54-006 ENSP00000412534 ENST00000458278	H7C3L3 [Direct mapping] Ankyrin repeat domain-containing protein 54 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	208 aa 23 kDa	No	0
ANKRD54-010 ENSP00000384392 ENST00000406423	B5MCX7 [Direct mapping] Ankyrin repeat domain-containing protein 54 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	180 aa 20.2 kDa	No	0
ANKRD54-013 ENSP00000477088 ENST00000609454	V9GYU2 [Direct mapping] Ankyrin repeat domain-containing protein 54 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		107 aa 12.7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.