Expression of HSCB in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

HscB mitochondrial iron-sulfur cluster co-chaperone

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA018447

GENE INFORMATION
Gene name	HSCB (HGNC Symbol)
Synonyms	DNAJC20, HSC20, Jac1
Description	HscB mitochondrial iron-sulfur cluster co-chaperone (HGNC Symbol)
Entrez gene summary
Chromosome	22
Cytoband	q12.1
Chromosome location (bp)	28742031 - 28757515
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100209 (version 83.38)
Entrez gene	150274
UniProt	Q8IWL3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IWL3
Antibodypedia	HSCB antibodies

PROTEIN BROWSER

HSCB-001	HSCB-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HSCB-001 ENSP00000216027 ENST00000216027	Q8IWL3 [Direct mapping] Iron-sulfur cluster co-chaperone protein HscB, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005813 [centrosome] GO:0005886 [plasma membrane] GO:0006457 [protein folding] GO:0016226 [iron-sulfur cluster assembly] GO:0046872 [metal ion binding] GO:0051087 [chaperone binding] GO:0051259 [protein oligomerization] Show all	235 aa 27.4 kDa	No	0
HSCB-003 ENSP00000381914 ENST00000398941	B0QYH2 [Direct mapping] Iron-sulfur cluster co-chaperone protein HscB, mitochondrial; J-type co-chaperone HSC20, isoform CRA_c Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006457 [protein folding] GO:0051087 [chaperone binding] Show all	143 aa 16.5 kDa	No	0