Expression of POLDIP3 in cancer - Summary

CANCER ATLAS

Gene description

Polymerase (DNA-directed), delta interacting protein 3

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Testis cancer

STAINING SUMMARY

HPA018419

GENE INFORMATION
Gene name	POLDIP3 (HGNC Symbol)
Synonyms	KIAA1649, PDIP46
Description	Polymerase (DNA-directed), delta interacting protein 3 (HGNC Symbol)
Entrez gene summary	This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Chromosome	22
Cytoband	q13.2
Chromosome location (bp)	42583721 - 42614962
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100227 (version 83.38)
Entrez gene	84271
UniProt	Q9BY77 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BY77
Antibodypedia	POLDIP3 antibodies

PROTEIN BROWSER

POLDIP3-001	POLDIP3-002	POLDIP3-201	POLDIP3-202	POLDIP3-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
POLDIP3-001 ENSP00000252115 ENST00000252115	Q9BY77 [Direct mapping] Polymerase delta-interacting protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000346 [transcription export complex] GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0016607 [nuclear speck] GO:0016973 [poly(A)+ mRNA export from nucleus] GO:0035145 [exon-exon junction complex] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] GO:0045727 [positive regulation of translation] Show all	421 aa 46.1 kDa	No	0
POLDIP3-002 ENSP00000252116 ENST00000348657	Q9BY77 [Direct mapping] Polymerase delta-interacting protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000346 [transcription export complex] GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0016607 [nuclear speck] GO:0016973 [poly(A)+ mRNA export from nucleus] GO:0035145 [exon-exon junction complex] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] GO:0045727 [positive regulation of translation] Show all	392 aa 42.9 kDa	No	0
POLDIP3-201 ENSP00000343060 ENST00000339677	Q6R954 [Direct mapping] Polymerase delta interacting protein 46; Polymerase delta-interacting protein 3 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0043231 [intracellular membrane-bounded organelle] Show all	185 aa 20.1 kDa	No	0
POLDIP3-202 ENSP00000397927 ENST00000451060	F6VRR5 [Direct mapping] Polymerase delta-interacting protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	438 aa 48.1 kDa	No	0
POLDIP3-203 ENSP00000482500 ENST00000617178	Q8WUT1 [Direct mapping] POLDIP3 protein; Polymerase delta-interacting protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	229 aa 24.8 kDa	No	0