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RASD2

GENERAL INFORMATION

Gene name

 RASD2

Gene description

 RASD family, member 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (seminal vesicle)
GTEx:Tissue enriched (caudate)
FANTOM5:Tissue enriched (caudate)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA005839
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (seminal vesicle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (caudate)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (caudate)

GENE INFORMATION

Gene name

 RASD2 (HGNC Symbol)

Synonyms

 MGC:4834, Rhes, TEM2

Description

 RASD family, member 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a Ras-related protein that enriched in striatum. The product of this gene binds to GTP and possesses intrinsic GTPase activity. The gene belongs to the Ras superfamily of small GTPases. The exact function of this gene is unknown, but most striatum-specific mRNAs characterized to date encode components of signal transduction cascades. [provided by RefSeq, Jul 2008]

Chromosome

 22

Cytoband

 q12.3

Chromosome location (bp)

 35540868 - 35554001

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000100302 (version 83.38)

Entrez gene

 23551

UniProt

 Q96D21 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96D21

Antibodypedia

 RASD2 antibodies

PROTEIN BROWSER
RASD2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RASD2-001
ENSP00000216127
ENST00000216127
Q96D21 [Direct mapping]
GTP-binding protein Rhes
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Predicted intracellular proteins
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GO:0001963 [synaptic transmission, dopaminergic]
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007626 [locomotory behavior]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0031397 [negative regulation of protein ubiquitination]
GO:0031624 [ubiquitin conjugating enzyme binding]
GO:0031681 [G-protein beta-subunit binding]
GO:0033235 [positive regulation of protein sumoylation]
GO:0043949 [regulation of cAMP-mediated signaling]
GO:0051897 [positive regulation of protein kinase B signaling]
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 266 aa
30.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.