Cell atlas - FAM118A - The Human Protein Atlas

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FAM118A

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Intermediate filaments

Human cell
	Cytosol
	Intermediate Filaments

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GENERAL INFORMATION
Gene name	FAM118A
Gene description	Family with sequence similarity 118, member A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the intermediate filaments. In addition localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Intermediate filaments (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA003902
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the intermediate filaments. In addition localized to the cytosol.

Main location

Intermediate filaments (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA003902	U-2 OS	Nucleus
			Intermediate filaments
			Cytosol
	HPA003902	U-251 MG	Intermediate filaments
	HPA003902	U-251 MG	Cytosol

GENE INFORMATION
Gene name	FAM118A (HGNC Symbol)
Synonyms	bK268H5.C22.4, C22orf8, FLJ20635
Description	Family with sequence similarity 118, member A (HGNC Symbol)
Entrez gene summary
Chromosome	22
Cytoband	q13.31
Chromosome location (bp)	45308968 - 45341955
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100376 (version 83.38)
Entrez gene	55007
UniProt	Q9NWS6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NWS6
Antibodypedia	FAM118A antibodies

PROTEIN BROWSER

FAM118A-001	FAM118A-002	FAM118A-003	FAM118A-006	FAM118A-007	FAM118A-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM118A-001 ENSP00000216214 ENST00000216214	Q9NWS6 [Direct mapping] Protein FAM118A A0A024R4V3 [Target identity:100%; Query identity:100%] Chromosome 22 open reading frame 8, isoform CRA_b Show all	Phobius predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	357 aa 40.3 kDa	No	0
FAM118A-002 ENSP00000395892 ENST00000441876	Q9NWS6 [Direct mapping] Protein FAM118A A0A024R4V3 [Target identity:100%; Query identity:100%] Chromosome 22 open reading frame 8, isoform CRA_b Show all	Phobius predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	357 aa 40.3 kDa	No	0
FAM118A-003 ENSP00000385231 ENST00000405673	B0QY29 [Direct mapping] Protein FAM118A Show all	Phobius predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		202 aa 22.5 kDa	No	0
FAM118A-006 ENSP00000395194 ENST00000427777	B0QY28 [Direct mapping] Protein FAM118A Show all	Phobius predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		139 aa 15.6 kDa	No	0
FAM118A-007 ENSP00000388511 ENST00000452238	B0QY27 [Direct mapping] Protein FAM118A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		29 aa 3.2 kDa	No	0
FAM118A-008 ENSP00000389298 ENST00000424557	B0QY26 [Direct mapping] Protein FAM118A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		15 aa 1.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.