Cell atlas - KHNYN - The Human Protein Atlas

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KHNYN

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	KHNYN
Gene description	KH and NYN domain containing
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA003402
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

Nucleoplasm (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA003402	A-431	Nucleoplasm
	HPA003402	A-431	Cytosol
	HPA003402	RT4	Nucleoplasm
			Aggresome
			Cytosol
	HPA003402	U-2 OS	No staining

GENE INFORMATION
Gene name	KHNYN (HGNC Symbol)
Synonyms	KIAA0323
Description	KH and NYN domain containing (HGNC Symbol)
Entrez gene summary	This gene encodes a protein containing a ribonuclease NYN domain. The function of this protein has yet to be determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Chromosome	14
Cytoband	q12
Chromosome location (bp)	24429286 - 24441834
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100441 (version 83.38)
Entrez gene	23351
UniProt	O15037 (UniProt - Evidence at protein level)
neXtProt	NX_O15037
Antibodypedia	KHNYN antibodies

PROTEIN BROWSER

KHNYN-001	KHNYN-002	KHNYN-003	KHNYN-004	KHNYN-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KHNYN-001 ENSP00000450799 ENST00000553935	O15037 [Direct mapping] Protein KHNYN Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003723 [RNA binding] GO:0005575 [cellular_component] GO:0008150 [biological_process] Show all	678 aa 74.5 kDa	No	0
KHNYN-002 ENSP00000251343 ENST00000251343	O15037 [Direct mapping] Protein KHNYN Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003723 [RNA binding] GO:0005575 [cellular_component] GO:0008150 [biological_process] Show all	678 aa 74.5 kDa	No	0
KHNYN-003 ENSP00000451106 ENST00000556842	O15037 [Direct mapping] Protein KHNYN Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003723 [RNA binding] GO:0005575 [cellular_component] GO:0008150 [biological_process] Show all	678 aa 74.5 kDa	No	0
KHNYN-004 ENSP00000451004 ENST00000556510	G3V331 [Direct mapping] Protein KHNYN Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003723 [RNA binding] Show all	135 aa 15 kDa	No	0
KHNYN-005 ENSP00000451227 ENST00000554268	G3V3G3 [Direct mapping] Protein KHNYN Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		123 aa 14.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.