Cell atlas - RBM23 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	RBM23
Gene description	RNA binding motif protein 23
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	19
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the intermediate filaments. In addition localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Intermediate filaments (approved)
Additional location	In addition localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA004144
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the intermediate filaments. In addition localized to the nucleoplasm.

Main location

Intermediate filaments (approved)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA004144	A-431	Nucleoplasm
HPA004144	U-2 OS	Intermediate filaments
HPA004144	U-251 MG	Intermediate filaments

GENE INFORMATION
Gene name	RBM23 (HGNC Symbol)
Synonyms	CAPERbeta, FLJ10482, RNPC4
Description	RNA binding motif protein 23 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	22893206 - 22919184
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100461 (version 83.38)
Entrez gene	55147
UniProt	Q86U06 (UniProt - Evidence at protein level)
neXtProt	NX_Q86U06
Antibodypedia	RBM23 antibodies

PROTEIN BROWSER

RBM23-001	RBM23-002	RBM23-003	RBM23-006	RBM23-007	RBM23-010	RBM23-012	RBM23-015	RBM23-020	RBM23-021	RBM23-022	RBM23-023	RBM23-024	RBM23-025	RBM23-026	RBM23-027	RBM23-029	RBM23-030	RBM23-031

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBM23-001 ENSP00000352956 ENST00000359890	Q86U06 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0016020 [membrane] Show all	439 aa 48.7 kDa	No	0
RBM23-002 ENSP00000382806 ENST00000399922	Q86U06 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0016020 [membrane] Show all	423 aa 46.7 kDa	No	0
RBM23-003 ENSP00000339220 ENST00000346528	Q86U06 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0016020 [membrane] Show all	405 aa 44.5 kDa	No	0
RBM23-006 ENSP00000438504 ENST00000542016	G3XAP0 [Direct mapping] Probable RNA-binding protein 23; RNA binding motif protein 23, isoform CRA_f Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] Show all	269 aa 28.6 kDa	No	0
RBM23-007 ENSP00000452602 ENST00000555209	G3V5Z6 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	189 aa 19.8 kDa	No	0
RBM23-010 ENSP00000450558 ENST00000557549	G3V2B6 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		101 aa 11.8 kDa	No	0
RBM23-012 ENSP00000452538 ENST00000555691	G3V5V1 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		57 aa 6.3 kDa	No	0
RBM23-015 ENSP00000450672 ENST00000553876	G3V2H9 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		59 aa 6.5 kDa	No	0
RBM23-020 ENSP00000451838 ENST00000557245	H0YJN4 [Direct mapping] Probable RNA-binding protein 23 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 7.9 kDa	No	0
RBM23-021 ENSP00000452382 ENST00000557571	G3V5J5 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		91 aa 10.6 kDa	No	0
RBM23-022 ENSP00000451448 ENST00000554618	G3V3V3 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		75 aa 8.5 kDa	No	0
RBM23-023 ENSP00000452557 ENST00000556862	G3V5W6 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		92 aa 10.8 kDa	No	0
RBM23-024 ENSP00000451364 ENST00000555676	A0A0B4J267 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		100 aa 11.7 kDa	No	0
RBM23-025 ENSP00000451403 ENST00000557464	G3V3S8 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		66 aa 7.4 kDa	No	0
RBM23-026 ENSP00000450423 ENST00000557227	G3V225 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		21 aa 2.4 kDa	No	0
RBM23-027 ENSP00000450556 ENST00000555722	G3V2B4 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	51 aa 5.9 kDa	No	0
RBM23-029 ENSP00000451642 ENST00000553884	H0YJJ3 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	214 aa 22.3 kDa	No	0
RBM23-030 ENSP00000452583 ENST00000554256	G3V5Y2 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		144 aa 16.9 kDa	No	0
RBM23-031 ENSP00000452171 ENST00000557403	G3V546 [Direct mapping] Probable RNA-binding protein 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	115 aa 12.8 kDa	No	0