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TELO2

GENERAL INFORMATION

Gene name

 TELO2

Gene description

 Telomere maintenance 2

Protein class

 Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA041348 , HPA041473
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Small intestine

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 TELO2 (HGNC Symbol)

Synonyms

 hCLK2, KIAA0683, TEL2

Description

 Telomere maintenance 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.[provided by RefSeq, Mar 2009]

Chromosome

 16

Cytoband

 p13.3

Chromosome location (bp)

 1493344 - 1510457

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000100726 (version 83.38)

Entrez gene

 9894

UniProt

 Q9Y4R8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y4R8

Antibodypedia

 TELO2 antibodies

PROTEIN BROWSER
TELO2-001
TELO2-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TELO2-001
ENSP00000262319
ENST00000262319
Q9Y4R8 [Direct mapping]
Telomere length regulation protein TEL2 homolog
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000781 [chromosome, telomeric region]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0016020 [membrane]
GO:0031931 [TORC1 complex]
GO:0031932 [TORC2 complex]
GO:0032006 [regulation of TOR signaling]
GO:0032403 [protein complex binding]
GO:0032947 [protein complex scaffold]
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 837 aa
91.7 kDa 		No 1
TELO2-005
ENSP00000457461
ENST00000567423
H3BU45 [Direct mapping]
Telomere length regulation protein TEL2 homolog
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 160 aa
17.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.