Cell atlas - CPNE6 - The Human Protein Atlas

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CPNE6

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CPNE6
Gene description	Copine VI (neuronal)
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	13
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (U-266/84)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-266/84) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CPNE6
Synonyms
Description	Copine VI (neuronal) (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the copine family. Members of this family are calcium-dependent, phospholipid-binding proteins with C2 domains, two calcium- and phospholipid-binding domains. Through their domain structure and lipid binding capabilities, these proteins may play a role in membrane trafficking. This protein is thought to be brain-specific and has a domain structure of two N-terminal C2 domains and one von Willebrand factor A domain. It may have a role in synaptic plasticity. [provided by RefSeq, Jul 2013]
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	24070837 - 24078100
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100884 (version 83.38)
Entrez gene	9362
UniProt	O95741 (UniProt - Evidence at protein level)
neXtProt	NX_O95741
Antibodypedia	CPNE6 antibodies

PROTEIN BROWSER

CPNE6-003	CPNE6-009	CPNE6-010	CPNE6-011	CPNE6-012	CPNE6-013	CPNE6-014	CPNE6-015	CPNE6-016	CPNE6-017	CPNE6-018	CPNE6-019	CPNE6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CPNE6-003 ENSP00000380211 ENST00000397016	O95741 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001786 [phosphatidylserine binding] GO:0005215 [transporter activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005768 [endosome] GO:0005886 [plasma membrane] GO:0006629 [lipid metabolic process] GO:0006644 [phospholipid metabolic process] GO:0007268 [synaptic transmission] GO:0007399 [nervous system development] GO:0016020 [membrane] GO:0016192 [vesicle-mediated transport] GO:0030424 [axon] GO:0030425 [dendrite] GO:0043204 [perikaryon] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] GO:0070062 [extracellular exosome] GO:1903861 [positive regulation of dendrite extension] Show all	557 aa 62 kDa	No	0
CPNE6-009 ENSP00000453261 ENST00000560828	H0YLM2 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	158 aa 17.8 kDa	No	0
CPNE6-010 ENSP00000454075 ENST00000560761	H0YNM7 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	149 aa 16.5 kDa	No	0
CPNE6-011 ENSP00000453326 ENST00000558859	H0YLS9 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		26 aa 3.2 kDa	No	0
CPNE6-012 ENSP00000452884 ENST00000560884	H0YKP1 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	159 aa 18 kDa	No	0
CPNE6-013 ENSP00000452653 ENST00000559207	H0YK44 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	110 aa 12.9 kDa	No	0
CPNE6-014 ENSP00000454093 ENST00000558450	H0YNP2 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	131 aa 14.8 kDa	No	0
CPNE6-015 ENSP00000454192 ENST00000560356	H0YNX4 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	141 aa 15.7 kDa	No	0
CPNE6-016 ENSP00000453483 ENST00000559778	H0YM67 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	105 aa 12 kDa	No	0
CPNE6-017 ENSP00000454166 ENST00000557889	H0YNV2 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		52 aa 5.8 kDa	No	0
CPNE6-018 ENSP00000453352 ENST00000558541	H0YLV2 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	226 aa 25.7 kDa	No	0
CPNE6-019 ENSP00000452826 ENST00000559197	H0YKJ0 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	153 aa 17 kDa	No	0
CPNE6-201 ENSP00000440077 ENST00000537691	O95741 [Direct mapping] Copine-6 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001786 [phosphatidylserine binding] GO:0005215 [transporter activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005768 [endosome] GO:0005886 [plasma membrane] GO:0006629 [lipid metabolic process] GO:0006644 [phospholipid metabolic process] GO:0007268 [synaptic transmission] GO:0007399 [nervous system development] GO:0016020 [membrane] GO:0016192 [vesicle-mediated transport] GO:0030424 [axon] GO:0030425 [dendrite] GO:0043204 [perikaryon] GO:0044281 [small molecule metabolic process] GO:0045334 [clathrin-coated endocytic vesicle] GO:0046474 [glycerophospholipid biosynthetic process] GO:0070062 [extracellular exosome] GO:0071277 [cellular response to calcium ion] GO:1903861 [positive regulation of dendrite extension] Show all	612 aa 67.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.