Tissue expression of SEC23A - Summary - The Human Protein Atlas

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SEC23A

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SEC23A
Gene description	Sec23 homolog A, COPII coat complex component
Protein class	Disease related genes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several tissues.

DATA RELIABILITY
Data reliability description	Caution, targets protein from more than one gene. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA069974
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	SEC23A
Synonyms
Description	Sec23 homolog A, COPII coat complex component (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008]
Chromosome	14
Cytoband	q21.1
Chromosome location (bp)	39031919 - 39109646
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100934 (version 83.38)
Entrez gene	10484
UniProt	Q15436 (UniProt - Evidence at protein level)
neXtProt	NX_Q15436
Antibodypedia	SEC23A antibodies

PROTEIN BROWSER

SEC23A-001	SEC23A-002	SEC23A-006	SEC23A-009	SEC23A-010	SEC23A-011	SEC23A-012	SEC23A-013	SEC23A-018	SEC23A-020	SEC23A-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SEC23A-001 ENSP00000306881 ENST00000307712	Q15436 [Direct mapping] Protein transport protein Sec23A Show all	Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006886 [intracellular protein transport] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008270 [zinc ion binding] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0016192 [vesicle-mediated transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030868 [smooth endoplasmic reticulum membrane] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0048208 [COPII vesicle coating] GO:0048471 [perinuclear region of cytoplasm] GO:0061024 [membrane organization] Show all	765 aa 86.2 kDa	No	0
SEC23A-002 ENSP00000444193 ENST00000537403	Q15436 [Direct mapping] Protein transport protein Sec23A Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006886 [intracellular protein transport] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008270 [zinc ion binding] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0016192 [vesicle-mediated transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030127 [COPII vesicle coat] GO:0030868 [smooth endoplasmic reticulum membrane] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0048208 [COPII vesicle coating] GO:0061024 [membrane organization] Show all	563 aa 63.1 kDa	No	0
SEC23A-006 ENSP00000445393 ENST00000545328	F5H365 [Direct mapping] Protein transport protein Sec23A Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006886 [intracellular protein transport] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008270 [zinc ion binding] GO:0030127 [COPII vesicle coat] Show all	736 aa 83 kDa	No	0
SEC23A-009 ENSP00000452390 ENST00000557437	G3V5K1 [Direct mapping] Protein transport protein Sec23A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		40 aa 4.7 kDa	No	0
SEC23A-010 ENSP00000451230 ENST00000556092	G3V3G5 [Direct mapping] Protein transport protein Sec23A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006886 [intracellular protein transport] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008270 [zinc ion binding] GO:0030127 [COPII vesicle coat] Show all	140 aa 16.3 kDa	No	0
SEC23A-011 ENSP00000447489 ENST00000548032	G3V1W4 [Direct mapping] Protein transport protein Sec23A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006886 [intracellular protein transport] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008270 [zinc ion binding] GO:0030127 [COPII vesicle coat] Show all	108 aa 12.6 kDa	No	0
SEC23A-012 ENSP00000451924 ENST00000553970	G3V4Q2 [Direct mapping] Protein transport protein Sec23A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		86 aa 10.1 kDa	No	0
SEC23A-013 ENSP00000452575 ENST00000557280	G3V5X8 [Direct mapping] Protein transport protein Sec23A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		85 aa 10 kDa	No	0
SEC23A-018 ENSP00000451999 ENST00000555425	G3V4V1 [Direct mapping] Protein transport protein Sec23A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006886 [intracellular protein transport] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008270 [zinc ion binding] GO:0030127 [COPII vesicle coat] Show all	94 aa 11.1 kDa	No	0
SEC23A-020 ENSP00000450819 ENST00000555017	G3V2R6 [Direct mapping] Protein transport protein Sec23A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006886 [intracellular protein transport] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008270 [zinc ion binding] GO:0030127 [COPII vesicle coat] Show all	169 aa 19.4 kDa	No	0
SEC23A-201 ENSP00000486142 ENST00000625395	G3V4Q2 [Direct mapping] Protein transport protein Sec23A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		86 aa 10.1 kDa	No	0

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The Human Protein Atlas

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