Expression of UQCC1 in cancer - Summary

CANCER ATLAS

Gene description

Ubiquinol-cytochrome c reductase complex assembly factor 1

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA034875

GENE INFORMATION
Gene name	UQCC1 (HGNC Symbol)
Synonyms	BFZB, C20orf44, CBP3, FLJ10850, UQCC
Description	Ubiquinol-cytochrome c reductase complex assembly factor 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a transmembrane protein that is structurally similar to the mouse basic fibroblast growth factor repressed ZIC-binding protein. In mouse this protein may be involved in fibroblast growth factor regulated growth control. In humans, polymorphisms in this gene are associated with variation in human height and osteoarthritis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Chromosome	20
Cytoband	q11.22
Chromosome location (bp)	35302566 - 35412141
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101019 (version 83.38)
Entrez gene	55245
UniProt	Q9NVA1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NVA1
Antibodypedia	UQCC1 antibodies

PROTEIN BROWSER

UQCC1-003	UQCC1-005	UQCC1-006	UQCC1-007	UQCC1-010	UQCC1-012	UQCC1-017	UQCC1-018	UQCC1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UQCC1-003 ENSP00000399713 ENST00000424405	B1AKV3 [Direct mapping] Ubiquinol-cytochrome-c reductase complex assembly factor 1 Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		249 aa 28.9 kDa	No	0
UQCC1-005 ENSP00000380686 ENST00000397554	B1AKV2 [Direct mapping] Ubiquinol-cytochrome-c reductase complex assembly factor 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		221 aa 25.5 kDa	No	1
UQCC1-006 ENSP00000352161 ENST00000359226	B1AKV4 [Direct mapping] Ubiquinol-cytochrome-c reductase complex assembly factor 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		219 aa 24.9 kDa	No	0
UQCC1-007 ENSP00000398531 ENST00000438533	B1AKV6 [Direct mapping] Ubiquinol-cytochrome-c reductase complex assembly factor 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		243 aa 27.9 kDa	No	1
UQCC1-010 ENSP00000363506 ENST00000374385	Q9NVA1 [Direct mapping] Ubiquinol-cytochrome-c reductase complex assembly factor 1 Q3KRB6 [Target identity:100%; Query identity:100%] Chromosome 20 open reading frame 44, isoform CRA_g; Ubiquinol-cytochrome c reductase complex chaperone Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0034551 [mitochondrial respiratory chain complex III assembly] GO:0070131 [positive regulation of mitochondrial translation] Show all	299 aa 34.6 kDa	No	0
UQCC1-012 ENSP00000363505 ENST00000374384	Q9NVA1 [Direct mapping] Ubiquinol-cytochrome-c reductase complex assembly factor 1 Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005743 [mitochondrial inner membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0034551 [mitochondrial respiratory chain complex III assembly] GO:0070131 [positive regulation of mitochondrial translation] Show all	273 aa 31.5 kDa	No	0
UQCC1-017 ENSP00000335364 ENST00000349714	Q9NVA1 [Direct mapping] Ubiquinol-cytochrome-c reductase complex assembly factor 1 Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005743 [mitochondrial inner membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0034551 [mitochondrial respiratory chain complex III assembly] GO:0070131 [positive regulation of mitochondrial translation] Show all	272 aa 31.3 kDa	No	0
UQCC1-018 ENSP00000363501 ENST00000374380	Q9NVA1 [Direct mapping] Ubiquinol-cytochrome-c reductase complex assembly factor 1 Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005743 [mitochondrial inner membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0034551 [mitochondrial respiratory chain complex III assembly] GO:0070131 [positive regulation of mitochondrial translation] Show all	231 aa 27 kDa	No	0
UQCC1-201 ENSP00000380688 ENST00000397556	F6UTR7 [Direct mapping] Ubiquinol-cytochrome-c reductase complex assembly factor 1 Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		226 aa 26.2 kDa	No	0